G133

GR 89696 fumarate salt

solid

• Sinonimo/i: 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate salt
• Formula empirica (notazione di Hill): C₁₉H₂₅Cl₂N₃O₃ · C₄H₄O₄
• Numero CAS: 126766-32-3
• Peso molecolare: 530.40
• NACRES: NA.77
• PubChem Substance ID: 24278038
• UNSPSC Code: 12352200
• MDL number: MFCD00274044
• Form: solid

Proprietà

• form: solid
• Quality Segment: 100
• color: off-white
• solubility: ethanol: 4.0 mg/mL, DMSO: >50 mg/mL, H₂O: 8.5 mg/mL
• SMILES string: OC(=O)\C=C\C(O)=O.COC(=O)N1CCN(C(CN2CCCC2)C1)C(=O)Cc3ccc(Cl)c(Cl)c3
• InChI: 1S/C19H25Cl2N3O3.C4H4O4/c1-27-19(26)23-8-9-24(15(13-23)12-22-6-2-3-7-22)18(25)11-14-4-5-16(20)17(21)10-14;5-3(6)1-2-4(7)8/h4-5,10,15H,2-3,6-9,11-13H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
• InChI key: ABTNETSDXZBJTE-WLHGVMLRSA-N
• Gene Information: human ... OPRK1(4986)

Descrizione

Application

GR 89696 fumarate salt has been used as a κ κ2 opioid receptor (KOR) agonist to study its anti-scratching and antipruritic effects on monkeys.

Biochem/physiol Actions

GR 89696 fumarate is a selective κ2 opioid receptor agonist.

Legal Information

Sold for research purposes under agreement from Glaxo­Smith­Kline

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)