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G002

Isoguvacine hydrochloride

solid

Sinonimo/i:

1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid hydrochloride

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Voi/SKUDisponibilitàPrezzo
25 mg
Per conoscere la disponibilità, visualizza il carrello
CHF 84.70
100 mg
Per conoscere la disponibilità, visualizza il carrello
CHF 222.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C6H9NO2 · HCl
Numero CAS:
68547-97-7
Peso molecolare:
163.60
NACRES:
NA.77
PubChem Substance ID:
24278160
UNSPSC Code:
12352200
MDL number:
MFCD00055192
Form:
solid

CHF 84.70

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form

solid

Quality Segment

200

color

white

solubility

H2O: soluble (refrigerate if not used immediately.), methanol: slightly soluble, neutral and acidic solutions: stable (in basic solutions the free amine can oxidize easily)

SMILES string

Cl[H].OC(=O)C1=CCNCC1

InChI

1S/C6H9NO2.ClH/c8-6(9)5-1-3-7-4-2-5;/h1,7H,2-4H2,(H,8,9);1H

InChI key

SUWREQRNTXCCBL-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Application

Isoguvacine hydrochloride has been used as a γ-aminobutyric acid type A (GABAA) receptor agonist:
  • to study its effects on neuronal activity in rats
  • to study its antiallodynic effect in rats
  • to study its effects on baroreflex gains in rats

Biochem/physiol Actions

Isoguvacine is a strong γ-aminobutyric acid A (GABAA) receptor agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GABAA Receptors and GABAC Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Questo articolo
N7510N142SML2313
Isoguvacine hydrochloride solid

Sigma-Aldrich

G002

Isoguvacine hydrochloride

Nicardipine hydrochloride powder, ≥98%

Sigma-Aldrich

N7510

Nicardipine hydrochloride

NO-711 hydrochloride ≥98% (HPLC)

Sigma-Aldrich

N142

NO-711 hydrochloride

Higenamine hydrochloride ≥95% (HPLC)

Sigma-Aldrich

SML2313

Higenamine hydrochloride

description

solid

description

powder, ≥98%

description

≥98% (HPLC)

description

≥95% (HPLC)

form

solid

form

powder

form

powder

form

powder

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

-

solubility

neutral and acidic solutions: stable (in basic solutions the free amine can oxidize easily), methanol: slightly soluble, H2O: soluble (refrigerate if not used immediately.)

solubility

methanol: soluble, H2O: slightly soluble, 0.1 M NaOH: insoluble, DMSO: ~1 mg/mL

solubility

H2O: 10 mg/mL at 60 °C

solubility

H2O: 2 mg/mL, clear (warmed)

color

white

color

yellow

color

-

color

white to beige

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Gene Information

human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)

Gene Information

human ... GABBR1(2550), GABBR2(9568), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Gene Information

-

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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