F7016

Flumequine

≥97.0% (HPLC)

• Sinonimo/i: 9-Fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid
• Formula empirica (notazione di Hill): C₁₄H₁₂FNO₃
• Numero CAS: 42835-25-6
• Peso molecolare: 261.25
• UNSPSC Code: 51102829
• NACRES: NA.85
• PubChem Substance ID: 24894926
• EC Number: 255-962-6
• Beilstein/REAXYS Number: 490724
• MDL number: MFCD00079298

Proprietà

• assay: ≥97.0% (HPLC)
• form: powder
• color: white to off-white
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: DNA synthesis | interferes, enzyme | inhibits
• SMILES string: CC1CCc2cc(F)cc3C(=O)C(=CN1c23)C(O)=O
• InChI: 1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)
• InChI key: DPSPPJIUMHPXMA-UHFFFAOYSA-N

Descrizione

General description

Chemical structure: fluoroquinolone

Biochem/physiol Actions

Flumequine inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited .

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)