F3418

Monoclonal Anti-Cytokeratin, pan−FITC antibody produced in mouse

clone C-11, purified immunoglobulin, buffered aqueous solution

• Sinonimo/i: Monoclonal Anti-Pan Cytokeratin
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Coniugato: FITC conjugate
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: C-11, monoclonal
• Stato: buffered aqueous solution
• Reattività contro le specie: bovine, mouse, frog, human, kangaroo rat, rat
• Condizioni di stoccaggio: protect from light
• tecniche: direct immunofluorescence: 1:50 using PtK₂ cells; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50 using human placenta; western blot: suitable
• Isotipo: IgG1
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: bovine ... Krt1(100301161) ; human ... KRT1(3848) , KRT13(3858) , KRT13(3858) , KRT18(3875) , KRT18(3875) , KRT4(3851) , KRT4(3851) , KRT5(3852) , KRT5(3852) , KRT6A(3868) , KRT6A(3868) , KRT6B(3854) , KRT6B(3854) , KRT8(3856) , KRT8(3856) ; mouse ... Krt1(16678) , Krt10(16661) , Krt10(16661) , Krt13(16663) , Krt13(16663) , Krt18(16668) , Krt18(16668) , Krt4(16682) , Krt4(16682) , Krt5(110308) , Krt5(110308) , Krt6a(16687) , Krt6a(16687) , Krt6b(16688) , Krt6b(16688) , Krt8(16691) , Krt8(16691) ; rat ... Krt1(300250) , Krt1-18(706059) , Krt1-18(706059) , Krt10(450225) , Krt10(450225) , Krt2-5(369017) , Krt2-5(369017) , Krt2-8(25626) , Krt2-8(25626)

Descrizione

Descrizione generale

Cytokeratins are the intermediate filaments of endocrine cells. These proteins belong to the intermediate filament (10 nm) superfamily of cytoskeletal proteins. Cytokeratins are the largest and most complex group of intermediate filaments. The family consists of at least 30 proteins with molecular weights ranging from 40kDa to 68kDa.

Immunogeno

keratin-enriched preparation from cultured human epidermoid carcinoma cell line A431.

Applicazioni

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunohistochemistry (1 paper)

Monoclonal Anti-Cytokeratin, pan−FITC antibody has been used in immunocytochemistry and has also been used to visualize lung epithelial cells.

Azioni biochim/fisiol

Cytokeratins helps in subtyping several kinds of epithelial differentiation or for narrowing possible sites of origin for metastatic carcinomas. Cytokeratins may play an important role in transhepatic transport and canalicular secretion.

Stato fisico

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)