F1428

Fenvalerate

≥97%

• Sinonimo/i: α-Cyano-3-phenoxybenzyl α-(4-chlorophenyl)­iso­valerate
• Formula empirica (notazione di Hill): C₂₅H₂₂ClNO₃
• Numero CAS: 51630-58-1
• Peso molecolare: 419.90
• UNSPSC Code: 12352200
• NACRES: NA.77
• PubChem Substance ID: 329799681
• MDL number: MFCD00055324
• Beilstein/REAXYS Number: 2025982
• Assay: ≥97%

Proprietà

• Quality Segment: 200
• assay: ≥97%
• storage temp.: −20°C
• SMILES string: CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3
• InChI: 1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3
• InChI key: NYPJDWWKZLNGGM-UHFFFAOYSA-N

Descrizione

General description

Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.

Application

Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.

Biochem/physiol Actions

Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.

Type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B).

Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes.

Preparation Note

Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS09
• Parola di avvertenza: Danger
• Codici di pericolo: H301,H315,H319,H335,H410
• Avvertenze di sicurezza: P261 - P264 - P273 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable