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EHU159091

Sigma-Aldrich

MISSION® esiRNA

targeting human GPR17

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20 μG
CHF 249.00
50 μG
CHF 443.00

CHF 249.00

Spedizione prevista il18 aprile 2025

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20 μG
CHF 249.00
50 μG
CHF 443.00

About This Item

Codice UNSPSC:
41105324
NACRES:
NA.51

CHF 249.00

Spedizione prevista il18 aprile 2025

Descrizione

Powered by Eupheria Biotech

Livello qualitativo

100

Nome Commerciale

MISSION®

Stato

lyophilized powder

Sequenza bersaglio del cDNA di esiRNA

GGGCTTGTGATGGCTACAATGGCTCCTAGACACTCAACGACTTCATCTGTGGCAGGGAGAGAGGAGGCCGGAAGAACAACCCCTGAACAATGGAGGCCTTTCTTTCCCGCTAGGCTCCCAGCCTCCTTCCCGCTACAGAATCGCTCATCGGCGAGGCTCAGCAGAAAGACCCTGAAGGCAGGCTGCAAATGACCCAGAAGAGGGACCTGGGAGTCCTGGTGGGGACGGGGAGGGAGTCTCAATACTCCTTTGCAGTGCAAGGTACTCTGAGTCCCCTCTGTAGTGCCTCTGCCAGACACACACTGCCTGAGTTGAAGAGACACAGGCCACACA

N° accesso Ensembl | uomo

ENSG00000144230

N° accesso NCBI

NM_005291

Condizioni di spedizione

ambient

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... GPR17(2840) , GPR17(2840)

Descrizione generale

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Note legali

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

10 - Combustible liquids

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Simona Cosentino et al.
Journal of cellular and molecular medicine, 18(9), 1785-1796 (2014-06-10)
GPR17 is a G(i) -coupled dual receptor activated by uracil-nucleotides and cysteinyl-leukotrienes. These mediators are massively released into hypoxic tissues. In the normal heart, GPR17 expression has been reported. By contrast, its role in myocardial ischaemia has not yet been
Zhangfu Wang et al.
International immunopharmacology, 88, 106870-106870 (2020-08-18)
Osteoarthritis (OA) is a common joint disease affecting millions of elderly people worldwide. However, the mechanism of OA is complicated and remains poorly understood. Thus, a safe and effective therapeutic strategy has yet to be developed. G protein-coupled receptor 17
Bing Zhao et al.
International journal of molecular medicine, 42(5), 2750-2762 (2018-09-19)
GPR17 is a G (i)-coupled dual receptor, linked to P2Y and CysLT receptors stimulated by uracil nucleotides and cysteinyl leukotrienes, respectively. Recent evidence has demonstrated that GPR17 inhibition ameliorates the progression of cerebral ischemic injury by regulating neuronal death and

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