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EHU054231

Sigma-Aldrich

MISSION® esiRNA

targeting human BCL3

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20 μG
CHF 249.00
50 μG
CHF 443.00

CHF 249.00

Spedizione prevista il30 maggio 2025

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20 μG
CHF 249.00
50 μG
CHF 443.00

About This Item

Codice UNSPSC:
41105324
NACRES:
NA.51

CHF 249.00

Spedizione prevista il30 maggio 2025

Descrizione

Powered by Eupheria Biotech

Nome Commerciale

MISSION®

Stato

lyophilized powder

Sequenza bersaglio del cDNA di esiRNA

CTTCCTTCCTTCCCCATCTCCACCCGCCTTCCTGCCCTTTGCTGGGGTCCTCCGAGGCCCTGGCCGGCCGGTGCCCCCCTCCCCAGCTCCAGGAGGCAGCTGAGGGGGATGGGGGGGCAGATCTTGGACTCATGAGGAGGGGCCCCCCTGCCCTGTGGGGTCAACCCTTCTGGAAACTGTGAAGATCTCACTCTGCCCCCCCCCCCCATCTTCGGGACCAGGATTTGCACAGAAGCACATGCACCTACCCATACACCCCCTCTTCTGAGCACAGATGTTCCCCCATCTCGCTCCCTCCCAGGACTCTGACCCCAGCATTCTCAGGCACCAGTCCCTGTCCGGAATGCCACCCACATCTTCCATTTCCATGTCCCCTCCCAGAGCTGGTGGACCCAGGGAACAGCCACTCCCCTCCACTCTCTACCAGATAACTGAGGAGGGGAGAGGTG

N° accesso Ensembl | uomo

ENSG00000069399

N° accesso NCBI

NM_005178

Condizioni di spedizione

ambient

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... BCL3(602) , BCL3(602)

Descrizione generale

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Note legali

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

10 - Combustible liquids

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Mikiko Tohyama et al.
European journal of immunology, 48(1), 168-179 (2017-09-14)
IL-22 induces STAT3 phosphorylation and mediates psoriasis-related gene expression. However, the signaling mechanism leading from pSTAT3 to the expression of these genes remains unclear. We focused on Bcl-3, which is induced by STAT3 activation and mediates gene expression. In cultured
SeungPil Yun et al.
Biomolecules & therapeutics, 26(5), 464-473 (2017-08-24)
Cripto is a small glycosylphosphatidylinositol-anchored signaling protein that can detach from the anchored membrane and stimulate proliferation, migration, differentiation, vascularization, and angiogenesis. In the present study, we demonstrated that Cripto positively affected proliferation and survival of mesenchymal stem cells (MSCs)
Kangsheng Tu et al.
Oncology reports, 35(4), 2382-2390 (2016-02-18)
Previous studies have demonstrated the aberrant expression and oncogenic role of B-cell CLL/lymphoma-3 (BCL-3) in human malignancies. However, the clinical significance of BCL-3 and its biological function in human hepatocellular carcinoma (HCC) remain unknown. In the present study, the expression
Xi Chen et al.
Cell death & disease, 7(12), e2508-e2508 (2016-12-03)
Transforming growth factor beta (TGFβ) signaling in breast cancer is selectively associated with pulmonary metastasis. However, the underlying mechanisms remain unclear. Here we show that Bcl-3, a member of the IκB family, serves as a critical regulator in TGFβ signaling
Junhaohui Huo et al.
Acta biochimica et biophysica Sinica, 50(11), 1141-1149 (2018-10-06)
Bcl-3 is an established oncogene in diverse malignant tumors. In this study, we investigated a dual role of Bcl-3 in BL1-subtype triple-negative breast cancer (TNBC). The BL1-subtype TNBC is featured by increasing cell cycle gene expression and the highest sensitivity
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