Passa al contenuto
Merck
Tutte le immagini(3)

Documenti fondamentali

E4018

Sigma-Aldrich

(−)-Epicatechin

≥98% (HPLC), from green tea

Sinonimo/i:

(−)-cis-3,3′,4′,5,7-Pentahydroxyflavane, (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali

Scegli un formato

1 MG
CHF 51.50
5 MG
CHF 180.00

CHF 51.50


Spedizione prevista il29 maggio 2025


Richiedi un ordine bulk

Scegli un formato

Cambia visualizzazione
1 MG
CHF 51.50
5 MG
CHF 180.00

About This Item

Formula empirica (notazione di Hill):
C15H14O6
Numero CAS:
Peso molecolare:
290.27
Beilstein:
92760
Numero CE:
Numero MDL:
Codice UNSPSC:
12352205
ID PubChem:
NACRES:
NA.77

CHF 51.50


Spedizione prevista il29 maggio 2025


Richiedi un ordine bulk

Origine biologica

green tea

Saggio

≥98% (HPLC)

Punto di fusione

240 °C (dec.) (lit.)

applicazioni

metabolomics
vitamins, nutraceuticals, and natural products

Temperatura di conservazione

2-8°C

Stringa SMILE

O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1
PFTAWBLQPZVEMU-UKRRQHHQSA-N

Informazioni sul gene

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Epicatechin is a flavanol, that belongs to the class of secondary, polyphenolic plant metabolites.[1]

Applicazioni

(-)-Epicatechin has been used:
  • to examine its biological effects in cell lines from human gender-specific cancers[2]
  • to study its antiviral activity[3]
  • to test its ability to regenerate this enzymatic activity both in vitro at the isolated MPO−H2O2−Cl- system and ex vivo in human polymorphonuclear leukocytes (PMNs)[4]

Azioni biochim/fisiol

This antioxidant is found in chocolate. (-)-Epicatechin is linked with cardiovascular effects. It is considered as a dependable standard due to its availability in cacao seeds and cocoa products.[5] The halogenating activity of myeloperoxidase can be restored by (-)-epicatechin.[4]

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Divergent antiviral effects of bioflavonoids on the hepatitis C virus life cycle
Khachatoorian R, et al.
Virology, 346-355 (2012)
Epicatechins purified from green tea (Camellia sinensis) differentially suppress growth of gender-dependent human cancer cell lines
Ravindranath M H, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM, 3(2), 237-247 (2006)
Fluorescent detection of (-)-epicatechin in microsamples from cacao seeds and cocoa products: Comparison with Folin-Ciocalteu method
Ramirez-Sanchez I, et al.
Journal of Food Lipids, 23(8), 790-793 (2010)
(-)-Epicatechin regenerates the chlorinating activity of myeloperoxidase in vitro and in neutrophil granulocytes
Flemmig J, et al.
Journal of Inorganic Biochemistry, 84-91 (2014)
(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
Schroeter H, et al.
Proceedings of the National Academy of Sciences of the USA, 103(4), 1024-1029 (2006)

Articoli

DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.