E125
β-Estradiol
Sinonimo/i:
1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin
Autenticati per visualizzare i prezzi organizzativi e contrattuali.
Scegli un formato
Cambia visualizzazione
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C18H24O2
Numero CAS:
Peso molecolare:
272.38
EC Number:
200-023-8
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1914275
MDL number:
Servizio Tecnico
Hai bisogno di aiuto? Il nostro team di scienziati qualificati è a tua disposizione.
Permettici di aiutartimp
176-180 °C (lit.)
storage temp.
2-8°C
SMILES string
O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C
InChI
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InChI key
VOXZDWNPVJITMN-ZBRFXRBCSA-N
Gene Information
human ... ESR1(2099)
Biochem/physiol Actions
The major estrogen secreted by the premenopausal ovary.
The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.
Still not finding the right product?
Explore all of our products under β-Estradiol
Classe di stoccaggio
10 - Combustible liquids
wgk
WGK 1
flash_point_f
188.6 °F
flash_point_c
87 °C
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Scegli una delle versioni più recenti:
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior.
Pascal Pigeon et al.
Journal of medicinal chemistry, 48(8), 2814-2821 (2005-04-15)
A series of ruthenocene derivatives, 1-[4-(O(CH(2))(n)()N(CH(3))(2))phenyl]-1-(4-hydroxyphenyl)-2-ruthenocenylbut-1-ene, with n = 2-5, based on the structure of the breast cancer drug tamoxifen has been prepared. These compounds were obtained, via a McMurry cross-coupling reaction, as a mixture of Z and E isomers
Artem Cherkasov et al.
Journal of medicinal chemistry, 49(25), 7466-7478 (2006-12-08)
A combination of protein-ligand docking and ligand-based QSAR approaches has been elaborated, aiming to speed-up the process of virtual screening. In particular, this approach utilizes docking scores generated for already processed compounds to build predictive QSAR models that, in turn
James S Wright et al.
Journal of medicinal chemistry, 54(2), 433-448 (2010-12-31)
Long-term use of estrogen supplements by women leads to an increased risk of breast and uterine cancers. Possible mechanisms include metabolism of estradiol and compounds related to tumor-initiating quinones, and ligand-induced activation of the estrogen receptors ERα and ERβ which
Numero articolo commerciale globale
| SKU | GTIN |
|---|---|
| SAB1306163-400UL | 04061835631612 |