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Merck

D8399

Danazol

≥98%

Sinonimo/i:

17β-Hydroxy-2,4,17α-pregnadien-20-yno[2,3-d]isoxazole, 2,4,17α-Pregnadien-20-yno[2,3-d]­isoxa­zol-17-ol

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100 MG

CHF 95.30

250 MG

CHF 381.00

1 G

CHF 730.00

CHF 95.30

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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C22H27NO2
Numero CAS:
17230-88-5
Peso molecolare:
337.46
NACRES:
NA.77
PubChem Substance ID:
24277708
UNSPSC Code:
51111800
EC Number:
241-270-1
MDL number:
MFCD00056838
Assay:
≥98%
Form:
powder
Quality level:
200

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InChI key

POZRVZJJTULAOH-ZIKCMSSPSA-N

InChI

1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16?,17?,18?,20?,21?,22-/m0/s1

SMILES string

CC12Cc3cnoc3C=C1CCC4C2CCC5(C)C4CC[C@@]5(O)C#C

assay

≥98%

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

Quality Level

200

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Questo articolo
SML2344G5168SML3135
Danazol ≥98%

Sigma-Aldrich

D8399

Danazol

SJB3-019A ≥98% (HPLC)

Sigma-Aldrich

SML2344

SJB3-019A

(Z)-Guggulsterone ≥89% (HPLC), powder

Sigma-Aldrich

G5168

(Z)-Guggulsterone

Cinobufagin ≥98% (HPLC)

Sigma-Aldrich

SML3135

Cinobufagin

form

powder

form

powder

form

powder

form

powder

assay

≥98%

assay

≥98% (HPLC)

assay

≥89% (HPLC)

assay

≥98% (HPLC)

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

drug control

-

drug control

-

drug control

-

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

100

originator

Sanofi Aventis

originator

-

originator

-

originator

-

Biochem/physiol Actions

Danazol is a weak androgen; anterior pituitary suppressant.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 2

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
BCCN6582
BCCM9049
BCCJ9969
BCCH0214
BCCG4030

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Allergy and asthma proceedings, 29(3), 225-231 (2008-04-05)
Hereditary angioedema (HAE) is an autosomal dominant disease characterized by painful, recurrent attacks of inflammation affecting the hands, feet, face, abdomen, urogenital tract, and the larynx. The inflammation can be disfiguring, debilitating, quite painful, and, in the case of laryngeal
E Miller
Seminars in veterinary medicine and surgery (small animal), 12(3), 167-169 (1997-08-01)
Currently available therapeutic protocols for immune-mediated diseases in dogs and cats can be associated with poor response rates and a high incidence of side effects. The development of multidrug protocols often results in a synergistic effect that more efficiently suppresses
H Farkas et al.
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Hereditary angioedema is a potentially life-threatening disorder, because edema occurring in the mucosa of the upper airways can lead to suffocation. The management of HAE consists of avoiding the triggering factors, prophylaxis, and the acute treatment of edematous episodes. Medical
Pagalavan Letchumanan et al.
Seminars in arthritis and rheumatism, 40(4), 298-306 (2010-06-15)
To review and summarize published information on the use, effectiveness, and adverse effects of danazol in patients with systemic lupus erythematosus (SLE). A MEDLINE search from January 1950 to July 2009 was conducted using 2 search strategies retrieving 51 and
E Hughes et al.
The Cochrane database of systematic reviews, (1)(1), CD000069-CD000069 (2007-01-27)
The synthetic androgen Danazol, was developed in the 1970's as a treatment for endometriosis. Its use was soon advocated in women with unexplained subfertility. Two randomised trials were subsequently conducted to assess the effectiveness of danazol in this population. The
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