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D4540

Dimetil solfossido

Name: Dimetil solfossido
Brand: SIGMA
Price: 68.9 CHF

≥99.5% (GC), suitable for plant cell culture

1 of 2 reviewers received a sample product or took part in a promotion

Sinonimo/i:

DMSO

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A voi/SKU	Disponibilità	Prezzo
100 mL	Per conoscere la disponibilità, visualizza il carrello	CHF 68.90
500 mL	Per conoscere la disponibilità, visualizza il carrello	CHF 168.00
1 L	Per conoscere la disponibilità, visualizza il carrello	CHF 282.00

Informazioni su questo articolo

Formula condensata:

(CH₃)₂SO

Numero CAS:

67-68-5

Peso molecolare:

78.13

UNSPSC Code:

12191502

NACRES:

NA.71

PubChem Substance ID:

24893881

EC Number:

200-664-3

Beilstein/REAXYS Number:

506008

MDL number:

MFCD00002089

Assay:

≥99.5% (GC)

Technique(s):

cell culture | plant: suitable, cryopreservation: suitable

Bp:

189 °C (lit.)

Vapor pressure:

0.42 mmHg ( 20 °C)

CHF 68.90

Per conoscere la disponibilità, visualizza il carrello

Servizio Tecnico

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Proprietà

Quality Segment

200

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

assay

≥99.5% (GC)

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

cell culture | plant: suitable, cryopreservation: suitable

impurities

<0.1% water (Karl Fischer)

color

colorless

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H₂O: miscible (completely)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Descrizione

Application

Il dimetilsolfossido è stato usato:

nella preparazione del bisfenolo A (BPA)
nel saggio di proliferazione cellulare (saggio MTT)
nel saggio di chemiosensibilità
come eccipiente di controllo in tutti gli esperimenti del tipo del saggio di apoptosi
nel saggio dell′etossiresorufina-O-deetilazione (EROD)

Biochem/physiol Actions

Il DMSO (dimetilsolfossido) è un solvente organico dotato di diverse attività farmaceutiche, come l′effetto analgesico, diuretico, batteriostatico, di penetrazione nelle membrane, antinfiammatorio, vasodilatatore e inibitorio della colinesterasi. È un sottoprodotto dell′industria del legname ed è usato come solvente industriale. Il DMSO è utile anche come agente terapeutico nel trattamento della cistite interstiziale e dell′artrite.

Other Notes

Vincitore del CiteAb Award 2024 per i fornitori che hanno conseguito risultati nella ricerca sul Parkinson

Disclaimer

Si sottoraffredda facilmente e rifonde lentamente a temperatura ambiente. Il prodotto solidificato può liquefarsi nuovamente senza subire danni se riscaldato a temperatura ambiente.

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1 of 1

Questo articolo	D2650	D2653	01934
Sigma-Aldrich D4540 Dimetil solfossido	Sigma-Aldrich D2650 Dimetil solfossido	Sigma-Aldrich D2653 Dimetil solfossido	Supelco 01934 Dimetil solfossido
description ≥99.5% (GC), suitable for plant cell culture	description Hybri-Max^™, sterile-filtered, BioReagent, suitable for hybridoma, ≥99.7%	description Hybri-Max^™, 0.2 μm filtered, BioReagent, suitable for hybridoma, ≥99.7%, Ampoule	description for inorganic trace analysis, ≥99.99995% (metals basis)
technique(s) cell culture \| plant: suitable, cryopreservation: suitable	technique(s) cell culture \| hybridoma: suitable, cryopreservation: suitable	technique(s) cell culture \| hybridoma: suitable, cryopreservation: suitable	technique(s) -
Quality Level 200	Quality Level 400	Quality Level 300	Quality Level 100
assay ≥99.5% (GC)	assay ≥99.7%	assay ≥99.7%	assay ≥99.9% (GC), ≥99.99995% (metals basis)
solubility H₂O: miscible (completely)	solubility H₂O: miscible (completely)	solubility H₂O: miscible (completely)	solubility H₂O: miscible (completely)
form liquid	form liquid	form liquid	form liquid
bp 189 °C (lit.)	bp 189 °C (lit.)	bp 189 °C (lit.)	bp 189 °C

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Classe di stoccaggio

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number

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Questions

1–10 of 11 Questions

2 years ago

Can I use this product (suitable for plant cell culture) for cyropreservation of mammalian cells? Does cryopreservation of mammalian cells require sterile-filtered DMSO?

1 answer
1. Technical Support
  
  2 years ago
  
  D4540 is listed as suitable for cryopreservation.
  However, D2650 is already pre-sterile and has documentation with a protocol for cryopreservation of human and animal cell lines.
  See these links:
  https://www.sigmaaldrich.com/product/sigma/d2650
  https://www.sigmaaldrich.com/product/sigma/d2650#product-documentation
  Look for the Product Information Sheet. Also, see this link for more information:
  https://www.sigmaaldrich.com/products/cell-culture-and-analysis/cell-culture-supplements-and-reagents/cell-freezing-reagents
  
  Helpful?
3 years ago

Can I autoclave this product?

1 answer
1. Technical Support
  
  3 years ago
  
  DMSO is not autoclavable in neat form. It is highly unlikely that microorganisms would survive in this environment. Should sterilization be necessary a PTFE, Polypropylene, or Nylon filter membrane are recommended for sterile-filtration.
  
  Helpful?
Anonymous

4 years ago

What is the DMSO dissolved in?

1 answer
1. Technical Support
  
  4 years ago
  
  DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.
  
  Helpful?
Anonymous

4 years ago

Dimethyl sulfoxide (DMSO) should be a liquid. Why did it arrive as a solid?

1 answer
1. Technical Support
  
  4 years ago
  
  DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.
  
  Helpful?
Anonymous

4 years ago

Where does DMSO come from?

1 answer
1. Technical Support
  
  4 years ago
  
  DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.
  
  Helpful?
Anonymous

4 years ago

What type of filter is used to sterile-filter Dimethyl sulfoxide (DMSO)?

1 answer
1. Technical Support
  
  4 years ago
  
  DMSO can be sterile-filtered through a 0.2 micron PTFE filter. The sterility testing is per the current US Pharmacopoeia method.
  
  Helpful?
Anonymous

4 years ago

What is the molarity of DMSO?

1 answer
1. Technical Support
  
  4 years ago
  
  DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.
  
  Helpful?
Anonymous

4 years ago

Is Dimethyl sulfoxide a sterile product?

1 answer
1. Technical Support
  
  4 years ago
  
  No, this product is not considered sterile. Product Nos. D2560 and D2438 are sterile-filtered.
  
  Helpful?
Anonymous

4 years ago

What concentration of DMSO do I use in a cell freezing media?

1 answer
1. Technical Support
  
  4 years ago
  
  DMSO is usually used at 1-10%, depending on the cell line. For the cell freezing media that we offer, it is used at 8.7% concentration.
  
  Helpful?
Anonymous

4 years ago

Does DMSO have any synthetic utility?

1 answer
1. Technical Support
  
  4 years ago
  
  DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.
  
  Helpful?