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D4007

5,5-Diphenylhydantoin

≥98%

Sinonimo/i:

5,5-Diphenyl-2,4-imidazolidinedione, Phenytoin

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Voi/SKUDisponibilitàPrezzo
5 g
Per conoscere la disponibilità, visualizza il carrello
CHF 41.20
100 g
Per conoscere la disponibilità, visualizza il carrello
CHF 56.20

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C15H12N2O2
Numero CAS:
57-41-0
Peso molecolare:
252.27
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
24278370
EC Number:
200-328-6
Beilstein/REAXYS Number:
384532
MDL number:
MFCD00005264
Assay:
≥98%
Form:
powder

CHF 41.20

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Quality Segment

100

assay

≥98%

form

powder

mp

293-295 °C (lit.)

solubility

DMSO: soluble

SMILES string

O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3

InChI

1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)

InChI key

CXOFVDLJLONNDW-UHFFFAOYSA-N

Gene Information

human ... CNR1(1268), CNR2(1269), CYP2C9(1559), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Faah(29347), Scn1a(81574), Scnn1g(24768), Slc6a1(79212)

General description

5,5-Diphenylhydantoin is an anticonvulsant, which is used to treat tonic-clonic seizures, complex partial seizures and neurosurgical related seizures. It induces osteoblast proliferation and differentiation. 5,5-Diphenylhydantoin used to treat epilepsy. It reduces the hyperexcitability of tissues and may be associated with cerebellar atrophy.

Application

5,5-Diphenylhydantoin has been used for phenytoin treatment. It has also been used to slow down or prevent mesoendoderm cell migration.

Biochem/physiol Actions

Anticonvulsant.
Reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.

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Questo articolo
P12900001535507T2573
5,5-Diphenylhydantoin ≥98%

Sigma-Aldrich

D4007

5,5-Diphenylhydantoin

Phenytoin European Pharmacopoeia (EP) Reference Standard

P1290000

Phenytoin

Phenytoin sodium United States Pharmacopeia (USP) Reference Standard

USP

1535507

Phenytoin sodium

Troglitazone ≥98% (HPLC)

Sigma-Aldrich

T2573

Troglitazone

description

≥98%

description

European Pharmacopoeia (EP) Reference Standard

description

United States Pharmacopeia (USP) Reference Standard

description

≥98% (HPLC)

assay

≥98%

assay

-

assay

-

assay

≥98% (HPLC)

form

powder

form

-

form

-

form

powder

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

200

solubility

DMSO: soluble

solubility

-

solubility

-

solubility

DMSO: 20 mg/mL

Gene Information

human ... CNR1(1268), CNR2(1269), CYP2C9(1559), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Faah(29347), Scn1a(81574), Scnn1g(24768), Slc6a1(79212)

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Gene Information

human ... PPARA(5465), PPARG(5468)

mp

293-295 °C (lit.)

mp

293-295 °C (lit.)

mp

-

mp

-

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

Classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

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