D3758
DL-2,4-Diaminobutyric acid dihydrochloride
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Informazioni su questo articolo
Formula condensata:
NH2CH2CH2CH(NH2)COOH · 2HCl
Numero CAS:
Peso molecolare:
191.06
UNSPSC Code:
12352200
NACRES:
NA.26
PubChem Substance ID:
EC Number:
265-774-6
Beilstein/REAXYS Number:
4708499
MDL number:
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Permettici di aiutartiassay
≥98% (TLC)
form
powder
color
white
mp
197 °C (dec.) (lit.)
application(s)
detection
storage temp.
−20°C
SMILES string
Cl.Cl.NCCC(N)C(O)=O
InChI
1S/C4H10N2O2.2ClH/c5-2-1-3(6)4(7)8;;/h3H,1-2,5-6H2,(H,7,8);2*1H
InChI key
CKAAWCHIBBNLOJ-UHFFFAOYSA-N
Biochem/physiol Actions
DL-2,4-Diaminobutyric acid is a racemic mixture of the selective GABA uptake inhibitors L-DABA and D-DABA. DL-2,4-diaminobutyric acid is found in cell-wall peptidoglycan of Leifsonia bigeumensis sp. Nov.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1
Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Sandra M Leal et al.
Journal of neurobiology, 61(2), 189-208 (2004-09-25)
We have identified specific GABAergic-modulated behaviors in the juvenile stage of the fruit fly, Drosophila melanogaster via systemic treatment of second instar larvae with the potent GABA transport inhibitor DL-2,4-diaminobutyric acid (DABA). DABA significantly inhibited motor-controlled body wall and mouth
Amanda J Foss et al.
Toxicon : official journal of the International Society on Toxinology, 152, 150-159 (2018-08-14)
β-Methylamino-L-alanine (BMAA) has been identified as the potential cause of the amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS/PDC) observed in the Chamorro people of Guam. The principal hypothesis for BMAA exposure and intoxication relies on the biomagnification of BMAA in flying fox
Syed G Dastager et al.
International journal of systematic and evolutionary microbiology, 58(Pt 8), 1935-1938 (2008-08-05)
A Gram-positive, motile, mesophilic bacterium that formed yellowish-white, circular, convex, glistening colonies, strain MSL-27T, was isolated from a soil sample from Bigeum Island, Korea, and its taxonomic position was investigated by a polyphasic approach. Cells of strain MSL-27T are non-spore-forming
Sandra M Leal et al.
Journal of neurobiology, 50(3), 245-261 (2002-01-26)
We have identified several GABAergic-modulated behaviors in Drosophila melanogaster by employing a pharmacological approach to disrupt GABA transporter function in vivo. Systemic treatment of adult female flies with the GABA transport inhibitors DL-2,4-diaminobutyric acid (DABA) or R,S-nipecotic acid (NipA), resulted
Aifeng Li et al.
Toxicon : official journal of the International Society on Toxinology, 151, 129-136 (2018-07-22)
In recent years, the neurotoxin β-N-methylamino-L-alanine (BMAA) has been reported in some marine mollusk species. To further discover BMAA in marine animals, a total of 59 samples belonging to 3 phyla, 22 families, and 43 species, were collected from Dalian
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