D1881

Dexamethasone 21-acetate

≥99%

• Sinonimo/i: 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate
• Formula empirica (notazione di Hill): C₂₄H₃₁FO₆
• Numero CAS: 1177-87-3
• Peso molecolare: 434.50
• Beilstein: 2342608
• Numero CE: 214-646-8
• Numero MDL: MFCD00027407
• Codice UNSPSC: 51422333
• ID PubChem: 24893562
• NACRES: NA.77

Proprietà

• Saggio: ≥99%
• Forma fisica: powder
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1; AKUJBENLRBOFTD-RPRRAYFGSA-N
• Informazioni sul gene: human ... NR3C1(2908)

Descrizione

Applicazioni

Dexamethasone 21-acetate has been used:

• as a component of the induction medium for the treatment of mice preadipocytes (5A) cells
• as a synthetic glucocorticoid to study its effects on the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in placentas of human and mice
• as a component of the complete medium for the culturing of porcine hepatocytes

Azioni biochim/fisiol

Dexamethasone 21-acetate or dexamethasone acetate is a derivative of dexamethasone. It is a hydrophobic drug. Dexamethasone is a glucocorticoid possessing anti-inflammatory activity.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H360FD
• Consigli di prudenza: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves