D003
R(−)-Apocodeine hydrochloride
solid
Sinonimo/i:
R(−)-10-Methoxy-11-hydroxyaporphine hydrochloride
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Informazioni su questo articolo
Formula empirica (notazione di Hill):
C18H19NO2 · HCl
Numero CAS:
Peso molecolare:
317.81
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Servizio Tecnico
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Permettici di aiutartiform
solid
optical activity
[α]22/D −43° in methanol(lit.)
color
off-white
solubility
H2O: soluble
storage temp.
2-8°C
SMILES string
Cl[H].[H][C@]12Cc3ccc(OC)c(O)c3-c4cccc(CCN1C)c24
Gene Information
human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)
Biochem/physiol Actions
Dopamine receptor agonist; apomorphine metabolite.
Disclaimer
Photosensitive
Classe di stoccaggio
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Gessa, et al., eds.
Apomorphine and Other Dopaminomimetics, Vols. 1 and 2 (1981)
R van der Geest et al.
Journal of chromatography. B, Biomedical sciences and applications, 702(1-2), 131-141 (1998-02-04)
Analytical methods are described for the selective, rapid and sensitive determination of R- and S-apomorphine, apocodeine and isoapocodeine and the glucuronic acid and sulfate conjugates in plasma and urine. The methods involve liquid-liquid extraction followed by high-performance liquid chromatography with
R V Smith et al.
Journal of natural products, 46(1), 79-91 (1983-01-01)
A solid basis for the M4-approach has been developed over the past 10 years. Recent examples of the production of difficult-to-synthesize mammalian metabolites through microbial transformations attest to the utility of the methodology. There is, however, much more to be