About This Item
Formula empirica (notazione di Hill):
C22H26N2O5S
Numero CAS:
Peso molecolare:
430.52
Numero MDL:
Codice UNSPSC:
12352200
Temperatura di conservazione
2-8°C
Stringa SMILE
CSCCC(NC(=O)C(Cc1ccccc1)NC(=O)OCc2ccccc2)C(O)=O
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J D Williams et al.
Journal of immunology (Baltimore, Md. : 1950), 136(2), 642-648 (1986-01-01)
The N-formylated tripeptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) initiated the generation of immunoreactive C-6 sulfidopeptide leukotrienes and of leukotriene B4 (LTB4) in a dose-dependent manner from monolayers of human monocytes pretreated for 10 min with 5 micrograms/ml of cytochalasin B. The EC50 for
Generation of hydrogen peroxide by human neutrophils: effects of soluble stimuli and requirements for divalent cations.
R J Smith et al.
Clinical immunology and immunopathology, 24(2), 194-203 (1982-08-01)
S C Speziale et al.
Clinical immunology and immunopathology, 36(1), 60-69 (1985-07-01)
We report here that the chemotactic peptide, N-formyl-methionyl-leucyl-phenylalanine (FMLP), and the mitogenic phorbol ester, phorbol myristate acetate (PMA) cause a time- and concentration-dependent, selective, extracellular release of N-acetyl-beta-glucosaminidase and lysozyme from freshly isolated, adherent human peripheral blood monocytes. The inability
Pepstatin A-induced degranulation and superoxide anion generation by human neutrophils.
R J Smith et al.
Clinical immunology and immunopathology, 22(1), 83-93 (1982-01-01)
G Marone et al.
Agents and actions, 16(5), 306-309 (1985-07-01)
Pepstatin A, a pentapeptide isolated from cultures of actinomycetes, induced histamine secretion from human basophils in the concentration range of 3 X 10(-7) to 10(-4) M. The characteristics of this reaction were similar to those of f-met-peptide-induced histamine release: pepstatin
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