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C5135

Castor Oil, Ethoxylated

pH range 6.0-8.0

Sinonimo/i:

EL, Macrogolglycerol ricinoleate, PEG-35 castor oil, Polyoxyl-35 castor oil

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Voi/SKUDisponibilitàPrezzo
500 g
Per conoscere la disponibilità, visualizza il carrello
CHF 212.00
1 kg
Per conoscere la disponibilità, visualizza il carrello
CHF 374.00

Informazioni su questo articolo

Numero CAS:
UNSPSC Code:
12161902
NACRES:
NA.25
MDL number:

CHF 212.00


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description

non-ionic

Quality Segment

form

liquid

mol wt

~2500 g/mol

pH range

6.0-8.0

HLB

12 - 14

application(s)

sample preservation

SMILES string

ClCC(OC(=O)N)CCl

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

InChI key

JMNCUXPHXKHBPY-UHFFFAOYSA-N

General description

Castor Oil, Ethoxylated is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.
Castor Oil, Ethoxylated is polyethylene oxide surfactant and is viscous in nature. It has a hydrophobic-lipophilic balance value in the range of 12-14.

Application

Castor Oil, Ethoxylated has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.

Biochem/physiol Actions

Castor Oil, Ethoxylated is used in lipid-based formulations for drugs and solubilization of cosmetics. Castor Oil, Ethoxylated is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.

Other Notes

A derivative of castor oil and ethylene oxide.

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Questo articolo
309061547200238470
USP

USP

1547200

Polyoxyl 35 castor oil

Cremophor® EL

Millipore

238470

Cremophor® EL

description

pH range 6.0-8.0

description

-

description

United States Pharmacopeia (USP) Reference Standard

description

-

form

liquid

form

paste

form

-

form

liquid

application(s)

sample preservation

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

(Excipient in drug)

Quality Level

200

Quality Level

100

Quality Level

-

Quality Level

100

HLB

12 - 14

HLB

-

HLB

-

HLB

-

mol wt

~2500 g/mol

mol wt

-

mol wt

-

mol wt

-

description

non-ionic

description

non-ionic

description

-

description

-


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Classe di stoccaggio

10 - Combustible liquids

Punto di infiammabilità (°F)

494.6 °F - Not applicable

Punto di infiammabilità (°C)

257 °C - Not applicable

DPI (dispositivi di protezione individuale)

Eyeshields, Gloves



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Certificati d'analisi (COA)

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Questions

1–9 of 9 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Can this be stored in -20C?

    1 answer
    1. This product is to be stored at room temperature. Storing the product at freezer temperatures has not been evaluated and may cause degradation.

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  4. How much is the Cloud Point?

    1 answer
    1. The cloud point is not determined.

      Helpful?

  5. What is the hydrophile-lipophile balance (HLB) for Cremophor EL (Product No. C5135)?

    1 answer
    1. The manufacturer (BASF) reports an HLB value of between 12 and 14 for Cremophor EL (Product No. C5135).

      Helpful?

  6. How can Cremophor EL (Product No. C5135) be sterilized?

    1 answer
    1. The manufacturer (BASF) recommends that it be sterilized by heating in an autoclave for 30 minutes at 120°C. It may acquire a somewhat deeper color. Either the neat material or neutral aqueous solutions may be autoclaved.

      Helpful?

  7. What is the molecular weight of Cremophor EL (Product No. C5135)?

    1 answer
    1. The manufacturer (BASF) reports a molecular weight of approximately 2500 for Cremophor EL (Product No. C5135).

      Helpful?

  8. What solvents can I use to prepare a solution of Cremophor EL (Product No. C5135)? Or is it already in solution?

    1 answer
    1. Cremophor EL is a neat liquid, sold by weight. It is not already in solution. It is soluble in water; note that the solubility in water actually decreases with an increase in temperature. It is also soluble in many organic solvents, such as ethanol, isopropyl alcohol, chloroform and others.

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  9. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

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