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C3196

Sigma-Aldrich

S(−)-Cathinone hydrochloride

Sinonimo/i:

α-Aminopropiophenone hydrochloride, S(−)-2-Amino-1-phenyl-1-propanone hydrochloride

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About This Item

Formula empirica (notazione di Hill):
C9H11NO · HCl
Numero CAS:
71031-15-7
Peso molecolare:
185.65
Numero MDL:
MFCD00673264
Codice UNSPSC:
12352200
ID PubChem:
24892592
NACRES:
NA.77

Forma fisica

powder

Livello qualitativo

200

Controllo stupefacenti

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Solubilità

H2O: soluble
ethanol: soluble

applicazioni

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Temperatura di conservazione

2-8°C

Stringa SMILE

Cl.C[C@H](N)C(=O)c1ccccc1

InChI

1S/C9H11NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7H,10H2,1H3;1H/t7-;/m0./s1
HPZCAKYHISJOIK-FJXQXJEOSA-N

Categorie correlate

Descrizione generale

Cathinone is a monoamine alkaloid of Khat shrub. It is a β-keto derivative of amphetamine. Cathinone is structurally similar to dopamine and amphetamine. A synthetic cathinone is categorized as a new psychoactive substance.

Azioni biochim/fisiol

Cathinone is the major central nervous system stimulant. Like amphetamine, it is a potent releaser of norepinephrine and dopamine from their intracellular stores. Cathinone derivates are known to have prolonged effects on nervous and blood vascular systems. The mode of action of its derivative is by inhibiting the reuptake of neurotransmitters and stimulating cathinone-sensitive receptors.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H315,H319,H335

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificati d'analisi (COA)

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Marcin Rojkiewicz et al.
Forensic toxicology, 36(1), 141-150 (2018-01-26)
In this study, we performed identification and physicochemical characterization of two cathinone derivatives, 4-FPD and 4-MEAP, found in market-available materials. The compounds were characterized by electrospray ionization ion trap mass spectrometry (MS) in MS2 and MS3 modes, gas chromatography-MS, infrared
Toxicology and the clinical laboratory
Contemporary Practice in Clinical Chemistry, 913-947 (2020)
D J Calcagnetti et al.
Progress in neuro-psychopharmacology & biological psychiatry, 17(4), 637-649 (1993-07-01)
1. The objective of Exp. 1 was to determine whether intracerebroventricular (ICV) injection of cathinone CATH (8.0-32 micrograms) would produce a dose-dependent conditioned place preference (CPP) and/or activation in rats. Results indicate that rats conditioned with 16 or 32 micrograms
A E Fleckenstein et al.
European journal of pharmacology, 382(1), 45-49 (1999-11-11)
High-dose administrations of amphetamine, methamphetamine, cathinone, methcathinone or methylenedioxymethamphetamine rapidly decrease dopamine and serotonin transporter function in vivo, as assessed in striatal synaptosomes obtained from drug-treated rats. In contrast, high-dose injections of fenfluramine, cocaine or methylphenidate had little or no
Issues of false negative results in toxicology: difficult in detecting certain drugs and issues with detection of synthetic cathinone (bath salts), synthetic cannabinoids (spice), and other new psychoactive substances
Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction, 257-270 (2019)
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