The impurities that may be present in this product have not been identified. These impurites may include water and salts reminaining following the purification process.
C2755
Cortisone
synthetic, ≥95%, powder
Sinonimo/i:
17α,21-Dihydroxy-4-pregnene-3,11,20-trione, 17α-Hydroxy-11-dehydrocorticosterone, 4-Pregnene-17α,21-diol-3,11,20-trione, Kendall’s Compound E, Reichstein’s Substance Fa
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Informazioni su questo articolo
Formula empirica (notazione di Hill):
C21H28O5
Numero CAS:
Peso molecolare:
360.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
200-162-4
MDL number:
Beilstein/REAXYS Number:
1356062
Assay:
≥95%
Form:
powder
Prezzi e disponibilità al momento non sono disponibili
Servizio Tecnico
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Permettici di aiutartiNome del prodotto
Cortisone, ≥95%
biological source
synthetic
Quality Segment
sterility
non-sterile
assay
≥95%
form
powder
technique(s)
inhibition assay: suitable
mp
223-228 °C (dec.) (lit.)
solubility
chloroform: methanol (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
SMILES string
C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)CC(=O)[C@H]23
InChI
1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChI key
MFYSYFVPBJMHGN-ZPOLXVRWSA-N
Gene Information
human ... SERPINA6(866)
Application
Biochem/physiol Actions
Cortisone (11 dehydro 17 hydroxycortico-sterone) is an anti-inflammatory glucocorticoid that delays wound healing after surgeries. It postpones the healing process by affecting the appearance of inflammatory cells, ground substance, fibroblasts, collagen, regenerating capillaries, and epithelial migration. Glucocorticoids have anti-inflammatory, anti-allergic and immunosuppressive properties and are extensively used in treatment and therapy.
Cortisone is a glucocorticoid; a corticosterone analog that has approximately twice the anti-inflammatory potency as corticosterone but much lower Na2+ retention potency.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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Questo articolo | |||
|---|---|---|---|
| description ≥95% | description United States Pharmacopeia (USP) Reference Standard | description Pharmaceutical Secondary Standard; Certified Reference Material | description certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland |
| assay ≥95% | assay - | assay - | assay - |
| form powder | form - | form - | form - |
| Quality Level 200 | Quality Level - | Quality Level 300 | Quality Level 300 |
| storage temp. room temp | storage temp. −20°C | storage temp. -10 to -25°C | storage temp. 2-8°C |
| solubility chloroform: methanol (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow | solubility - | solubility - | solubility - |
| shipped in ambient | shipped in - | shipped in - | shipped in - |
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Parola di avvertenza
Warning
Codici di pericolo
Avvertenze di sicurezza
Hazard Classifications
Repr. 2
Classe di stoccaggio
11 - Combustible Solids
Che succede?
WGK 3
Punto di infiammabilità (°F)
Not applicable
Punto di infiammabilità (°C)
Not applicable
DPI (dispositivi di protezione individuale)
Eyeshields, Gloves, type N95 (US)
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What kind of impurities this product consists? According assays it is ≥95% cortisone. What compounds are included in remaining 5%?
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