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C1011

Sigma-Aldrich

N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate

≥97% (CHN)

Sinonimo/i:

N-Cyclohexyl-N′-(β-[N-methylmorpholino]ethyl)carbodiimide p-toluenesulfonate, CMC, CME-CDI

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About This Item

Formula empirica (notazione di Hill):
C14H26N3O · C7H7O3S
Numero CAS:
Peso molecolare:
423.57
Beilstein:
3872192
Numero CE:
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:

Saggio

≥97% (CHN)

Stato

powder

tecniche

ligand binding assay: suitable

Colore

white

Punto di fusione

109-111 °C

applicazioni

peptide synthesis

Temperatura di conservazione

−20°C

Stringa SMILE

Cc1ccc(cc1)S([O-])(=O)=O.C[N+]2(CCOCC2)CCN=C=NC3CCCCC3

InChI

1S/C14H26N3O.C7H8O3S/c1-17(9-11-18-12-10-17)8-7-15-13-16-14-5-3-2-4-6-14;1-6-2-4-7(5-3-6)11(8,9)10/h14H,2-12H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
GBCAVSYHPPARHX-UHFFFAOYSA-M

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Applicazioni

Water-soluble condensing reagent for peptide synthesis, reagent used for coupling ligands to carriers in affinity chromatography.

Azioni biochim/fisiol

N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide (CMCT) selectively modifies/derivitizes all pseudouridine, thiouridine and 2-methylthio-6-isopentenyladenosine nucleosides for detection by methods such as matrix-assisted laser desorption/ionization mass spectrometry. CMCT, a water-soluble condensing reagent for peptide synthesis, is used as a reagent for coupling ligands to carriers in affinity chromatography.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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M S Sloma et al.
Biochimica et biophysica acta, 1521(1-3), 30-38 (2001-11-03)
We have investigated possible interaction sites for mRNA, tRNA, translation factors and the nascent peptide on 5S, 5.8S and 28S rRNA in in vivo assembled translational active mouse ribosomes by comparing the chemical footprinting patterns derived from native polysomes, salt-washed
Mei-Hui Wang et al.
Journal of hepatology, 63(2), 370-377 (2015-03-24)
The asialoglycoprotein receptor on hepatocyte membranes recognizes the galactose residues of glycoproteins. We investigated the specificity, accuracy and threshold value of asialoglycoprotein receptor imaging for estimating liver reserve via scintigraphy using (111)In-hexavalent lactoside in mouse models. (111)In-hexavalent lactoside scintigraphy for
Renata A Castro et al.
SpringerPlus, 3, 382-382 (2014-08-12)
The mangrove ecosystem is a coastal tropical biome located in the transition zone between land and sea that is characterized by periodic flooding, which confers unique and specific environmental conditions on this biome. In these ecosystems, the vegetation is dominated
Yongjun Wei et al.
PloS one, 10(6), e0129921-e0129921 (2015-06-13)
Diverse cellulolytic bacteria are essential for maintaining high lignocellulose degradation ability in biogas digesters. However, little was known about functional genes and gene clusters of dominant cellulolytic bacteria in biogas digesters. This is the foundation to understand lignocellulose degradation mechanisms
Lan Zhang et al.
Science (New York, N.Y.), 295(5562), 2084-2088 (2002-02-23)
Group II self-splicing introns catalyze autoexcision from precursor RNA transcripts by a mechanism strikingly similar to that of the spliceosome, an RNA-protein assembly responsible for splicing together the protein-coding parts of most eukaryotic pre-mRNAs. Splicing in both cases initiates via

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