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CdO/CdA

B3805

Anti-Bone Morphogenetic Protein 5 antibody produced in goat

Name: Anti-Bone Morphogenetic Protein 5 antibody produced in goat
Brand: SIGMA

affinity isolated antibody, lyophilized powder

Sinonimo/i:

Anti-BMP-5

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About This Item

Numero MDL:

MFCD01864602

Codice UNSPSC:

51111800

NACRES:

NA.41

Origine biologica

goat

Livello qualitativo

100

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

lyophilized powder

Reattività contro le specie

human

tecniche

immunohistochemistry (frozen sections): 5-15 μg/mL
neutralization: suitable
western blot: 0.1 μg/mL

N° accesso UniProt

P22003

applicazioni

research pathology

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... BMP5(653)

Immunogeno

recombinant human BMP-5, expressed in NSO cells.

Azioni biochim/fisiol

Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. BMP5 is required for the development and fine tuning of the skeletal morphology.

Stato fisico

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Control of BMP gene expression by long-range regulatory elements.

Steven Pregizer et al.

Cytokine & growth factor reviews, 20(5-6), 509-515 (2009-11-11)

Much evidence suggests that "developmental regulator" genes, like those encoding transcription factors and signaling molecules, are typically controlled by many modular, tissue-specific cis-regulatory elements that function during embryogenesis. These elements are often far from gene coding regions and promoters. Bone

Bone morphogenetic proteins in the bovine oviduct: differential expression of BMP-5 in the isthmus during the estrous cycle.

Elina V García et al.

Theriogenology, 81(8), 1032-1041 (2014-03-04)

Bone morphogenetic proteins (BMPs) play a crucial role in mammalian reproduction, but little is known about their expression and function in the oviduct, where preimplantation events take place. In the present study, messenger RNA (mRNA) expression of BMPs was examined

BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk.

Kohei Miyazono et al.

Cytokine & growth factor reviews, 16(3), 251-263 (2005-05-06)

Bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta (TGF-beta) superfamily, bind to two different serine/threonine kinase receptors, and mediate their signals through Smad-dependent and Smad-independent pathways. Receptor regulated-Smad (R-Smad) proteins specific for the BMP pathways interact with various

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