B3412

Berberine hemisulfate salt

≥95%

• Sinonimo/i: Natural Yellow 18
• Formula condensata: C₂₀H₁₈NO₄ · 1/2SO₄
• Numero CAS: 633-66-9
• Peso molecolare: 384.39
• UNSPSC Code: 12171500
• NACRES: NA.32
• PubChem Substance ID: 24891718
• MDL number: MFCD00031743
• Colour Index Number: 75160
• Assay: ≥95%
• Form: powder
• Solubility: methanol: soluble

Proprietà

• Quality Segment: 100
• assay: ≥95%
• form: powder
• solubility: methanol: soluble
• SMILES string: [O-]S([O-])(=O)=O.COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC.COc6ccc7cc8-c9cc%10OCOc%10cc9CC[n+]8cc7c6OC
• InChI: 1S/2C20H18NO4.H2O4S/c2*1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;1-5(2,3)4/h2*3-4,7-10H,5-6,11H2,1-2H3;(H2,1,2,3,4)/q2*+1;/p-2
• InChI key: OJVABJMSSDUECT-UHFFFAOYSA-L

Descrizione

Application

Fluorescent stain for heparin in mast cells

Biochem/physiol Actions

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Parola di avvertenza: Warning
• Codici di pericolo: H302
• Avvertenze di sicurezza: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 3
• DPI (dispositivi di protezione individuale): dust mask type N95 (US), Eyeshields, Gloves