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B3383

Sigma-Aldrich

Benzidine dihydrochloride

≥99% (titration)

Sinonimo/i:

4,4′-Diaminobiphenyl dihydrochloride

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About This Item

Formula empirica (notazione di Hill):
C12H12N2 · 2HCl
Numero CAS:
531-85-1
Peso molecolare:
257.16
Beilstein:
3914846
Numero CE:
208-519-6
Numero MDL:
MFCD00040389
Codice UNSPSC:
12352116
ID PubChem:
24891713
NACRES:
NA.25

Saggio

≥99% (titration)

Stato

powder

Stringa SMILE

Cl[H].Cl[H].Nc1ccc(cc1)-c2ccc(N)cc2

InChI

1S/C12H12N2.2ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;;/h1-8H,13-14H2;2*1H
RUAXWVDEYJEWRY-UHFFFAOYSA-N

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Applicazioni

Benzidine (4,4′-Diaminobiphenyl) is an environmental genotoxin that posses increased risks of cancer to exposed people. Benzidine may be used as a reference material in procedures that analyze for benzidine. Benzidine can be used in studies on its mechanisms of genotoxicity.

Azioni biochim/fisiol

Tumor initiator in mammary glands of experimental animal.

Attenzione

Cancer suspect agent.

Avvertenze

Danger

Indicazioni di pericolo

H302,H350,H410

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
WE314499/1
E314499/1V
078K1153
083K2521
026K2509

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Nuclear Fast Red

Sigma-Aldrich

N8002

Nuclear Fast Red

o-Dianisidine peroxidase substrate

Sigma-Aldrich

D9143

o-Dianisidine

p-Phenylenediamine 98% (GC)

Sigma-Aldrich

P6001

p-Phenylenediamine

Copper(II) acetate powder, 99.99% trace metals basis

Sigma-Aldrich

517453

Copper(II) acetate

K C Morton et al.
Carcinogenesis, 2(8), 747-752 (1981-01-01)
To evaluate the role of metabolism in benzidine (BZ) carcinogenesis, BZ and 2 or its metabolites, N,N'-diacetylbenzidine and N-hydroxy-N,N'-diacetylbenzidine (NOHDABZ), were given by i.p. injection to female CD rats twice weekly for 4 weeks beginning at 30 days of age.
Jungsun Park et al.
American journal of industrial medicine, 52(8), 625-632 (2009-06-30)
Many corporations move their manufacturing facilities or technologies from developed to developing countries. Stringent regulations have made it costly for industries to operate in developed, industrialized countries. In addition, labor costs are high in these countries, and there is increasing
Jaroslaw Cendrowski et al.
eLife, 9 (2020-08-17)
Intracellular transport undergoes remodeling upon cell differentiation, which involves cell type-specific regulators. Bone morphogenetic protein 2-inducible kinase (BMP2K) has been potentially implicated in endocytosis and cell differentiation but its molecular functions remained unknown. We discovered that its longer (L) and
Yan Cao et al.
Stem cells and development, 24(22), 2660-2673 (2015-07-17)
Autophagy is required for hematopoietic stem cell multilineage differentiation, but the underlying mechanism is unknown. Using a conditional mouse model and human leukemia cells, we uncovered a mechanistic link between autophagy and hematopoietic stem cell differentiation. Loss of autophagy in
Jung Woo Lee et al.
Chemical communications (Cambridge, England), 48(3), 422-424 (2011-11-15)
We report a facile route to synthesize size tunable Fe(3)O(4) nanoparticles (NPs)-carbon nitride nanotube (CNNT) hybrids. These hybrids showing the water-soluble property are proven to exhibit ultra high peroxidase mimetic activity compared to those of pure NPs, where a colorless
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