B2643

Estere N-idrossisuccinimmidico dell′acido biotinammidoesanoico

≥98% (TLC), powder

• Sinonimo/i: (+)-Biotinammidocaproato di N-succinimmidile, 6-(biotinammido)esanoato di succinimmidile, Estere N-succinimmidilico dell’acido N-(+)-biotinil-6-amminocaproico, Estere NHS dell'acido N-(+)-biotinil-6-amminoesanoico, N-biotinil-6-amminocaproato di N-succinimmidile
• Formula empirica (notazione di Hill): C₂₀H₃₀N₄O₆S
• Numero CAS: 72040-63-2
• Peso molecolare: 454.54
• Beilstein: 3577403
• Numero MDL: MFCD00065502
• Codice UNSPSC: 12352203
• ID PubChem: 24891665
• NACRES: NA.46

Proprietà

• Saggio: ≥98% (TLC)
• Forma fisica: powder
• Solubilità: H₂O: ≤2 mg/mL (with sonication); DMF: 50 mg/mL (Stable up to 2 months in dry DMF.)
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C20H30N4O6S/c25-15(7-4-3-6-14-19-13(12-31-14)22-20(29)23-19)21-11-5-1-2-8-18(28)30-24-16(26)9-10-17(24)27/h13-14,19H,1-12H2,(H,21,25)(H2,22,23,29)/t13-,14-,19-/m0/s1; UVGHPGOONBRLCX-NJSLBKSFSA-N

Descrizione

Applicazioni

Biotinamidohexanoic acid N-hydroxysuccinimide ester has been used in the biotinylation of antibodies.

Azioni biochim/fisiol

Biotin is a label widely used in several biochemical applications and has a high affinity for avidin. A spacer chain is required to reduce steric hindrance while coupling biotin (a small molecule) to biopolymers (large molecules). Biotinamidohexanoic acid N-hydroxysuccinimide ester incorporates a 7-atom spacer with the N-succinimide leaving group. It can react with a primary amine in the pH range of 6.5-8.5. This biotinylation reagent incorporates an aminocaproyl spacer and thus can reduce the steric hindrance in binding avidin to some biotinylated compounds.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)