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Documenti fondamentali

B2144

Sigma-Aldrich

Boc-Tyr-D-Ala-Gly

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About This Item

Formula empirica (notazione di Hill):
C19H27N3O7
Numero CAS:
Peso molecolare:
409.43
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:

Temperatura di conservazione

−20°C

Stringa SMILE

CC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(O)=O

Azioni biochim/fisiol

Boc-Tyr-D-Ala-Gly is an N-terminal protected tripeptides useful in solid phase peptide synthesis (Boc-SPPS). Boc-Tyr-D-Ala-Gly may be used in the synthesis of opioid activity containing peptides such as biphalin molecule, enkephalins and tetrapeptide hydrazide.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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A molecular dynamics study on opioid activities of biphalin molecule.
Hsieh JY, Chiang TY, Chen JL, et al.
Journal of Molecular Biology, 17, 2455-2464 (2011)
Krisztina Csabafi et al.
Peptides, 32(8), 1656-1660 (2011-07-05)
The neuroendocrine and behavioral effects of Tyr-D-Ala-Gly-Phe-D-Nle-Arg-Phe (DADN), a more stable derivative of the endogenous opiate Met-enkephalin related peptide Met(5)-enkephalin-Arg(6)-Phe(7) were investigated in mice. The behavioral experiments consisted of monitoring the horizontal (square crossing) and vertical (rearing) locomotion in the
Claudia U Hjørringgaard et al.
Journal of peptide science : an official publication of the European Peptide Society, 18(3), 199-207 (2012-01-19)
Benzotriazole-based coupling reagents have dominated the last two decades of solid phase peptide synthesis. However, a growing interest in synthesizing complex peptides has stimulated the search for more efficient and low-cost coupling reagents, such as COMU which has been introduced
Nigel P Pedersen et al.
Journal of neurophysiology, 106(2), 731-740 (2011-05-20)
The rostral ventromedial medulla (RVM) is an important site of opioid actions and forms part of an analgesic pathway that projects to the spinal cord. The neuronal mechanisms by which opioids act within this brain region remain unclear, particularly in
M Schnölzer et al.
International journal of peptide and protein research, 40(3-4), 180-193 (1992-09-01)
Simple, effective protocols have been developed for manual and machine-assisted Boc-chemistry solid phase peptide synthesis on polystyrene resins. These use in situ neutralization [i.e. neutralization simultaneous with coupling], high concentrations (> 0.2 M) of Boc-amino acid-OBt esters plus base for

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