Passa al contenuto
Merck

B003

Chloroethylclonidine dihydrochloride

solid

Sinonimo/i:

2-[2,6-Dichloro(N-β-chloroethyl-N-methyl)-4-aminomethyl]phenylimino-2-imidazolidine dihydrochloride, CEC dihydrochloride

Autenticati per visualizzare i prezzi organizzativi e contrattuali.

Scegli un formato

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C13H17Cl3N4 · 2HCl
Numero CAS:
70107-07-2
Peso molecolare:
408.58
NACRES:
NA.32
PubChem Substance ID:
24278281
UNSPSC Code:
12352202
MDL number:
MFCD00055181

Documenti fondamentali

Visualizza tutta la documentazione
Servizio Tecnico
Hai bisogno di aiuto? Il nostro team di scienziati qualificati è a tua disposizione.
Permettici di aiutarti
Servizio Tecnico
Hai bisogno di aiuto? Il nostro team di scienziati qualificati è a tua disposizione.
Permettici di aiutarti

Nome del prodotto

Chloroethylclonidine dihydrochloride, solid

InChI

1S/C13H17Cl3N4.2ClH/c1-20(5-2-14)8-9-6-10(15)12(11(16)7-9)19-13-17-3-4-18-13;;/h6-7H,2-5,8H2,1H3,(H2,17,18,19);2*1H

SMILES string

Cl.Cl.CN(CCCl)Cc1cc(Cl)c(\N=C2/NCCN2)c(Cl)c1

InChI key

CZSAXNDACBPMAB-UHFFFAOYSA-N

form

solid

color

off-white

solubility

0.1 M NaOH: 1 mg/mL (Stable for 24 hours at 4 °C.)
H2O: 12 mg/mL (Stable for 24 hours at 4 °C.)
methanol: 17 mg/mL (Stable for 24 hours at 4 °C.)
aqueous base: unstable

Gene Information

human ... ADRA1B(147)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Biochem/physiol Actions

Irreversible α1B-adrenoceptor alkylating agent.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documenti section.

Se ti serve aiuto, non esitare a contattarci Servizio Clienti

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

G Leclerc et al.
British journal of pharmacology, 71(1), 5-9 (1980-01-01)
1 alpha-Adrenoceptor stimulant activity was determined for noradrenaline (NA), clonidine and a series of para-substituted derivatives of clonidine on rat aortic strips, a rat brain synaptosome preparation, and anaesthetized pithed rats. The effects on the blood pressure of intraventricular (i.c.v.)
L Xiao et al.
European journal of pharmacology, 347(2-3), 319-327 (1998-07-08)
We quantified and compared the rates at which chloroethylclonidine (CEC) inactivated cloned rat alpha1A, alpha1B-, and alpha1D-adrenoceptors. Membranes from cells transfected with one of the three cloned alpha1-adrenoceptors were incubated for various intervals with 100 microM chloroethylclonidine at 10 degrees
Yoav Litvin et al.
The European journal of neuroscience, 40(2), 2344-2351 (2014-05-28)
Research suggests a causal link between estrogens and mood. Here, we began by examining the effects of estradiol (E2 ) on rat innate and conditioned defensive behaviors in response to cat odor. Second, we utilized whole-cell patch clamp electrophysiological techniques
M Takanashi et al.
Naunyn-Schmiedeberg's archives of pharmacology, 343(6), 669-673 (1991-06-01)
The influence of the alpha 1b-adrenoceptor-selective antagonist chlorethylclonidine on the alpha 1-adrenergic positive inotropic effect and the phosphoinositide hydrolysis induced by phenylephrine was investigated in the rabbit ventricular myocardium. Pretreatment of membrane fractions derived from the rabbit ventricular muscle with

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica