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A9554

Sigma-Aldrich

Allatostatin IV

≥97% (HPLC)

Sinonimo/i:

Asp-Arg-Leu-Tyr-Ser-Phe-Gly-Leu-NH2

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About This Item

Formula empirica (notazione di Hill):
C45H68N12O12
Numero CAS:
Peso molecolare:
969.09
Numero MDL:
Codice UNSPSC:
12352202
ID PubChem:
NACRES:
NA.26

product name

Allatostatin IV, ≥97% (HPLC)

Saggio

≥97% (HPLC)

Forma fisica

powder

Colore

white

Temperatura di conservazione

−20°C

Stringa SMILE

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(N)=O

InChI

1S/C45H68N12O12/c1-24(2)17-31(38(47)63)52-36(60)22-51-40(65)33(19-26-9-6-5-7-10-26)55-44(69)35(23-58)57-43(68)34(20-27-12-14-28(59)15-13-27)56-42(67)32(18-25(3)4)54-41(66)30(11-8-16-50-45(48)49)53-39(64)29(46)21-37(61)62/h5-7,9-10,12-15,24-25,29-35,58-59H,8,11,16-23,46H2,1-4H3,(H2,47,63)(H,51,65)(H,52,60)(H,53,64)(H,54,66)(H,55,69)(H,56,67)(H,57,68)(H,61,62)(H4,48,49,50)/t29-,30-,31-,32-,33-,34-,35-/m0/s1
BYSKWCFHMJZUBY-POFDKVPJSA-N

Amino Acid Sequence

Asp-Arg-Leu-Tyr-Ser-Phe-Gly-Leu-NH2

Azioni biochim/fisiol

Allatostatin IV, an octapeptide amine, is a member of the allatoregulatory peptide family found in insects which either inhibit (allatostatins) or stimulate (allatotropins) juvenile hormone (JH) synthesis.
Inhibitor of juvenile hormone synthesis in insects.

Altre note

Sequence highly conserved within the six C-terminal amino acids.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Sabine Kreissl et al.
The Journal of comparative neurology, 518(9), 1391-1417 (2010-02-27)
Information transmission and processing in the brain is achieved through a small family of chemical neurotransmitters and neuromodulators and a very large family of neuropeptides. In order to understand neural networks in the brain it will be necessary, therefore, to
Zhentao Sheng et al.
Insect biochemistry and molecular biology, 37(1), 90-96 (2006-12-19)
In a previous study, allatotropic and allatostatic activities were observed in brain extract from the Eri silkworm, Samia cynthia ricini (Samcri) [Li, S., Jiang, R.-J., Cao, M.-X., 2002b. Allatotropic and allatostatic activities in brain extracts of the Eri silkworm, S.
N Audsley et al.
Journal of insect physiology, 54(6), 969-980 (2008-04-02)
Allatoregulatory peptides either inhibit (allatostatins) or stimulate (allatotropins) juvenile hormone (JH) synthesis by the corpora allata (CA) of insects. However, these peptides are pleitropic, the regulation of JH biosynthesis is not their only function. There are currently three allatostatin families
Liang Liang et al.
Cell, 181(7), 1680-1692 (2020-06-27)
Metabolism during pregnancy is a dynamic and precisely programmed process, the failure of which can bring devastating consequences to the mother and fetus. To define a high-resolution temporal profile of metabolites during healthy pregnancy, we analyzed the untargeted metabolome of

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