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A9285

α1-Antichymotrypsin from human plasma

≥92.5% (SDS-PAGE), lyophilized powder

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0.1 mg
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CHF 193.00

Informazioni su questo articolo

Numero CAS:
UNSPSC Code:
12352202
NACRES:
NA.61
MDL number:

CHF 193.00


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biological source

human plasma

Quality Segment

assay

≥92.5% (SDS-PAGE)

form

lyophilized powder

mol wt

55-66 kDa

technique(s)

microbiological culture: suitable

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... SERPINA3(12)

General description

α1-Antichymotrypsin (α1-ACT) is also known as serpin peptidase inhibitor, clade A member 3 (SERPINA3). It is a 68 kDa serine protease inhibitor, secreted by the liver. It belongs to the serpin superfamily of protease inhibitors. SERPINA3 is located on human chromosome 14q32.1.

Application

α1-Antichymotrypsin from human plasma has been used as a component in yeast extract peptone dextrose broth (YEPD) for biofilm dispersion assays.

Biochem/physiol Actions

Specific inhibitor of chymotrypsin-like serine proteases.
Specific inhibitor of chymotrypsin-like serine proteases. Promotes amyloid-β polymerization in vitro and in vivo. Levels in plasma and cerebrospinal fluid have been found to correlate with progression of dementia in Alzheimer′s patients and induce phosphorylation of tau protein in neurons.
α1-Antichymotrypsin (α1-ACT) can block the functions of various serine proteases like chymotrypsin and cathepsin G. It serves as a potential therapeutic target of endometrial carcinoma (EC).

Packaging

Package size based on protein content.

Physical form

Lyophilized powder containing Tris buffer salt and NaCl.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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Questo articolo
SAB5700962178196C8946
description

≥92.5% (SDS-PAGE), lyophilized powder

description

-

description

Acute-phase protein present at ~45 mg/100 ml in plasma.

description

lyophilized powder

biological source

human plasma

biological source

rabbit

biological source

-

biological source

human pancreas

assay

≥92.5% (SDS-PAGE)

assay

-

assay

≥95% (SDS-PAGE)

assay

-

Gene Information

human ... SERPINA3(12)

Gene Information

human ... SERPINA3(12)

Gene Information

-

Gene Information

human ... CTRB1(1504)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

form

lyophilized powder

form

liquid

form

solid

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


Classe di stoccaggio

11 - Combustible Solids

Che succede?

WGK 3

Punto di infiammabilità (°F)

Not applicable

Punto di infiammabilità (°C)

Not applicable



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