A9102

AH13205

≥98% (HPLC), oil

• Sinonimo/i: trans-2-(4-(1-Hydroxyhexyl)phenyl-5-oxocyclopentaneheptanoic acid
• Formula empirica (notazione di Hill): C₂₄H₃₆O₄
• Numero CAS: 148436-63-9
• Peso molecolare: 388.54
• Numero MDL: MFCD00797641
• Codice UNSPSC: 12352200
• ID PubChem: 329771031
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Forma fisica: oil
• Colore: pale yellow
• Solubilità: DMSO: >10 mg/mL
• Ideatore: GlaxoSmithKline
• Temperatura di conservazione: −20°C
• Stringa SMILE: CCCCCC(O)c1ccc(cc1)[C@H]2CCC(=O)[C@@H]2CCCCCCC(O)=O
• InChI: 1S/C24H36O4/c1-2-3-6-10-22(25)19-14-12-18(13-15-19)20-16-17-23(26)21(20)9-7-4-5-8-11-24(27)28/h12-15,20-22,25H,2-11,16-17H2,1H3,(H,27,28)/t20-,21-,22?/m1/s1; XMQKDOCUWFCMEJ-JAZPPYFYSA-N

Descrizione

Descrizione generale

AH13205 is EP₂ prostanoid receptor agonist. There are five types of prostanoid receptors, which are classified based on sensitivity to the five naturally-occuring prostanoid ligand. The EP type of receptor is further divided into four subgroups – EP₁, EP₂, EP₃ and EP₄. EP₂ activation results in vascular, bronchial and reproductive smooth muscle relaxation.

Azioni biochim/fisiol

AH13205 is a selective, low potency agonist for the EP₂ receptor. AH13205 has been shown to compete with Prostaglandin E2 (PGE2) for binding, resulting in the displacement of PGE2 binding.

Caratteristiche e vantaggi

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)