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A6656

Sigma-Aldrich

Anti-Human IgG (γ-chain specific)−Agarose antibody produced in goat

IgG fraction of antiserum, saline suspension

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About This Item

Numero MDL:
Codice UNSPSC:
12352203

Origine biologica

goat

Coniugato

agarose conjugate

Forma dell’anticorpo

IgG fraction of antiserum

Tipo di anticorpo

secondary antibodies

Clone

polyclonal

Forma fisica

saline suspension

Reattività contro le specie

human

Grado di funzionalizzazione

≥5 mg per mL

tecniche

Ouchterlony double diffusion: suitable

Capacità

0.6 mg/mL binding capacity

Temperatura di conservazione

2-8°C

modifica post-traduzionali bersaglio

unmodified

Descrizione generale

Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders.
Goat anti-human IgG (γ-chain specific)-agarose antibody is specific for human IgG when tested against purified human IgA, IgG, IgM, Bence Jones kappa, and Bence Jones lambda myeloma proteins.

Immunogeno

human IgG

Applicazioni

Goat anti-human IgG (γ-chain specific)-agarose antibody has been used for immunocapture assays. It can also be used for Ouchterlony double diffusion assays.
IgGs were depleted from normal human serum by incubation with 50 μl of agarose-linked rabbit anti-human antibody (A3543) for 90 minutes at 4°C.

Stato fisico

Suspension in 0.5 M NaCl containing preservative

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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J L Viallard et al.
Clinical chemistry, 36(11), 2000-2003 (1990-11-01)
We report an abnormal pattern for enolase (EC 4.2.1.11) isoenzymes in the serum of a patient with squamous cell lung carcinoma. The alpha alpha-isoenzyme was present but the alpha gamma form was not detected, and near the point of application
J Raper et al.
Infection and immunity, 67(4), 1910-1916 (1999-03-20)
Natural resistance of humans to the cattle pathogen Trypanosoma brucei brucei has been attributed to the presence in human serum of nonimmune factors that lyse the parasite. Normal human serum contains two trypanosome lytic factors (TLFs). TLF1 is a 500-kDa
C Papadea et al.
Critical reviews in clinical laboratory sciences, 27(1), 27-58 (1989-01-01)
Human IgG consists of two identical heavy (H) chains and two identical light (L) chains joined by interchain disulfide bridges. Heterogeneity in the amino acid sequences of the H and L polypeptides results in at least three types of IgG
F Cataldo et al.
Minerva pediatrica, 42(12), 509-514 (1990-12-01)
IgG are the most common isotype of Ig and include four subclasses which differ from one another in the following ways: their initial amino acid sequence, their physical and chemical properties and the different serum concentrations reached with age. Every

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