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A6150
α1-Antitrypsin from human plasma
salt-free, lyophilized powder
Sinonimo/i:
α1-Proteinase inhibitor
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Cambia visualizzazione
| Voi/SKU | Disponibilità | Prezzo |
|---|---|---|
25 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 413.00 |
100 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 1650.00 |
500 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 8260.00 |
Informazioni su questo articolo
Servizio Tecnico
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Permettici di aiutartibiological source
human plasma
Quality Segment
form
salt-free, lyophilized powder
concentration
≥60% (biuret)
technique(s)
inhibition assay: suitable
storage temp.
2-8°C
Gene Information
human ... ELA2(1991), ELANE(1991), SERPINA1(5265)
Biochem/physiol Actions
≤10 mg will inhibit 1.0 mg of trypsin with activity of 10,000 BAEE units per mg protein. ≤10 mg will inhibit approx. 1.0 mg of ·α-chymotrypsin with activity of 40-50 BTEE units per mg protein.
Serine protease inhibitor; inhibits trypsin, chymotrypsin and pancreatic and granulocytic elastase, and acrosin. Effective concentration equimolar with proteinase.
Serine protease inhibitor; inhibits trypsin, chymotrypsin and pancreatic and granulocytic elastase, and acrosin. Effective concentration equimolar with proteinase.The effects of hereditary α1-antitrypsin deficiency and certain autoimmune states result from uncontrolled proteolysis in vivo. Direct α1-antitrypsin replacement therapy has shown promise in animal models of Type 1 diabetes.
Preparation Note
Chromatographically prepared and partially purified.
Disclaimer
Aqueous stock solutions containing 0.01% NaN3 are stable for several months. Solutions can be stored at −80 °C, but should not be refrozen. Unstable below pH 5.5. Inactivated by some non-serine proteinases and by oxidation of active site methionine residue.
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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| description salt-free, lyophilized powder | description salt-free, lyophilized powder | description IgG fraction of antiserum | description α1-Antitrypsin, CAS 9041-92-3, is a protease inhibitor of the serpin superfamily. Inhibits elastase, cathepsin G, and proteinase 3. |
| biological source human plasma | biological source human plasma | biological source rabbit | biological source - |
| Gene Information human ... ELA2(1991), ELANE(1991), SERPINA1(5265) | Gene Information human ... ELA2(1991), SERPINA1(5265) | Gene Information human ... SERPINA1(5265) | Gene Information - |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| form salt-free, lyophilized powder | form salt-free, lyophilized powder | form - | form solid |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. - |
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Classe di stoccaggio
11 - Combustible Solids
Che succede?
WGK 3
Punto di infiammabilità (°F)
Not applicable
Punto di infiammabilità (°C)
Not applicable
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What is the Department of Transportation shipping information for this product?
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What is the carbohydrate content of human alpha-1-Antitrypsin?
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We have found the information on alpha-1-antitrypsin in a reference book:The Plasma Proteins, F.W. Putnam, ed, volume 2, chapter 4, Table II.The alpha-1-antitrypsin is 12 percent carbohydrate, citing K. Heide and H.G. Schwick, Chemistry and Significance of the Carbohydrate Moieties of Human Serum Glycoproteins, Angew. Chem., Int. Ed. Eng., 12, 721-733 (1973).The table also gives information on the percentage of each type of monosaccharide that is present.
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