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A4929

Supelco

N,N′-Bis(acryloyl)cystamine

BioReagent, suitable for electrophoresis

Sinonimo/i:

2,2′-(Bisacrylamino)diethyl disulfide, BAC, Bis(2-acrylamidoethyl) disulfide

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5 G
CHF 547.00

CHF 547.00

Spedizione prevista il16 aprile 2025

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Cambia visualizzazione
5 G
CHF 547.00

About This Item

Formula empirica (notazione di Hill):
C10H16N2O2S2
Numero CAS:
60984-57-8
Peso molecolare:
260.38
Numero CE:
262-546-8
Numero MDL:
MFCD00036225
Codice UNSPSC:
12352116
ID PubChem:
24890926
NACRES:
NA.25

CHF 547.00

Spedizione prevista il16 aprile 2025

Nome Commerciale

BioReagent

Livello qualitativo

200

Stato

powder

Compatibilità

suitable for electrophoresis

Temperatura di conservazione

−20°C

Stringa SMILE

C=CC(=O)NCCSSCCNC(=O)C=C

InChI

1S/C10H16N2O2S2/c1-3-9(13)11-5-7-15-16-8-6-12-10(14)4-2/h3-4H,1-2,5-8H2,(H,11,13)(H,12,14)
DJVKJGIZQFBFGS-UHFFFAOYSA-N

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Applicazioni

BAC is used as a reversible cross-linker for polyacrylamide gels, to simplify isolation of macromolecules separated on the gels. The disulfide linkage can be broken with a suitable reducing agent. A 1-g slice of a 4% (12:1) gel will dissolve in 5 mL of 100 mM DTT in TBE (pH 8.3) in less than 30 min.
BAC is used as a reversible cross-linker for polyacrylamide gels. The disulfide linkage can be broken with a suitable reducing agent. A 12:1 ratio of acrylamide:BAC is recommended for DNA purification. A one gram slice of a 4% gel will dissolve in 5 mL of 100 mM DTT, TBE solution (pH 8.3) in less than 30 min. The pH of 8.3 is optimum for rapid dissolution of the gel.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
0000414165
0000414165
0000398898
0000360374
0000360374

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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PLoS genetics, 11(5), e1005209-e1005209 (2015-05-29)
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Sebastian Ribi et al.
Oncotarget, 6(10), 7727-7740 (2015-03-13)
Somatic mutations of TP53 are among the most common in cancer and germline mutations of TP53 (usually missense) can cause Li-Fraumeni syndrome (LFS). Recently, recurrent genomic rearrangements in intron 1 of TP53 have been described in osteosarcoma (OS), a highly
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