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A4562

Sigma-Aldrich

5-(N,N-Dimethyl)amiloride hydrochloride

Sinonimo/i:

3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride, DMA

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About This Item

Formula empirica (notazione di Hill):
C8H12ClN7O · HCl
Numero CAS:
1214-79-5
Peso molecolare:
294.14
Numero MDL:
MFCD00069207
Codice UNSPSC:
12352200
ID PubChem:
24278216
NACRES:
NA.77

Forma fisica

powder

Livello qualitativo

200

Temperatura di conservazione

2-8°C

Stringa SMILE

Cl.CN(C)c1nc(N)c(nc1Cl)C(=O)\N=C(\N)N

InChI

1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H
IIUPTHVVXMBJMQ-UHFFFAOYSA-N

Informazioni sul gene

human ... SCNN1A(6337) , SCNN1B(6338) , SCNN1D(6339) , SCNN1G(6340) , SLC9A1(6548)
mouse ... Scnn1a(20276) , Scnn1b(20277) , Scnn1d(140501) , Scnn1g(20278)
rat ... Scnn1a(25122) , Scnn1b(24767) , Scnn1g(24768) , Slc9a1(24782) , Slc9a2(24783) , Slc9a3(24784)

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Applicazioni

5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.

Azioni biochim/fisiol

Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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