A4316
Anantin from Streptomyces coerulescens
≥90% (HPLC)
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About This Item
Formula empirica (notazione di Hill):
C90H111N21O24
Numero CAS:
Peso molecolare:
1870.97
Numero MDL:
Codice UNSPSC:
12352200
Saggio
≥90% (HPLC)
Temperatura di conservazione
−20°C
Amino Acid Sequence
Cyclo(Gly-Phe-Ile-Gly-Trp-Gly-Asn-β-Asp)-Ile-Phe-Gly-His-Tyr-Ser-Gly-Asp-Phe
Azioni biochim/fisiol
Competitive antagonist at atrial natriuretic peptide NPR-A receptors.
Altre note
A cyclic peptide
Codice della classe di stoccaggio
13 - Non Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Nicholas W Baetz et al.
Investigative ophthalmology & visual science, 53(4), 2127-2132 (2012-03-20)
The retinal pigment epithelium (RPE) expresses aquaporin-1 (AQP1) and components of the natriuretic peptide signaling pathway. We hypothesized that stimulation of the natriuretic signaling pathway in RPE with atrial natriuretic peptide (ANP) and with membrane-permeable analogs of cGMP would induce
S Nachshon et al.
The American journal of physiology, 268(3 Pt 1), E428-E432 (1995-03-01)
Atrial natriuretic peptide (ANP) is a hormone-secreted predominantly by atrial myocytes. ANP exerts many of its actions via activation of the particulate guanylyl cyclase receptor ANPR-A and the formation of guanosine 3',5'-cyclic monophosphate (cGMP), which serves as a second messenger
Cell-specific manipulation of second messengers; a toolbox for integrative physiology in Drosophila.
Martin Kerr et al.
Current biology : CB, 14(16), 1468-1474 (2004-08-25)
Every living cell must detect, and respond appropriately to, external signals. The functions of intracellular second messengers, such as guanosine 3'5'-cyclic monophosphate (cGMP), adenosine 3'5'-cyclic monophosphate (cAMP), and intracellular calcium, are thus intensively studied. However, artifact-free manipulation of these messengers
R Vos et al.
Photochemistry and photobiology, 60(1), 24-32 (1994-07-01)
Anantin is a heptadecapeptide in which the C-terminal peptide chain pierces the covalently cyclized peptide ring formed by an amide link between the alpha-NH2 end group and the beta-carboxyl group of Asp(8). It contains a tryptophan and a histidine at
Neurohumoral mechanism in the natriuretic action of intracerebroventricular administration of renin.
Lida Zavala et al.
Journal of the renin-angiotensin-aldosterone system : JRAAS, 5(1), 39-44 (2004-05-12)
Intracerebroventricular (i.v.t.) administration of renin (R) decreases urinary volume and increases urinary sodium excretion. We investigated whether i.v.t.-R-induced natriuresis could be associated with the release of atrial natriuretic peptide (ANP), its interaction with renal ANP-A receptors (ANPR-A) and the subsequent
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