A3097

[Pro¹⁸, Asp²¹]-Amyloid β Protein Fragment 17-21 trifluoroacetate salt

≥98% (HPLC), solid

• Formula empirica (notazione di Hill): C₃₃H₄₃N₅O₈
• Numero CAS: 182912-74-9
• Peso molecolare: 637.72
• UNSPSC Code: 12352200
• MDL number: MFCD01862668

Proprietà

• assay: ≥98% (HPLC)
• form: solid
• UniProt accession no.: P05067
• storage temp.: −20°C
• SMILES string: CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CC(O)=O)C(O)=O
• Gene Information: human ... APP(351)

Descrizione

Biochem/physiol Actions

Inhibits amyloid formation in vitro and amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and blocks amyloid fibrial formation in rat brain.

Inhibits amyloid formation in vitro, prevents amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and completely blocks amyloid fibrial formation in rat brain.