A1980

A3 hydrochloride

≥98% (HPLC), solid

• Sinonimo/i: N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride
• Formula empirica (notazione di Hill): C₁₂H₁₃ClN₂O₂S · HCl
• Numero CAS: 78957-85-4
• Peso molecolare: 321.22
• NACRES: NA.77
• PubChem Substance ID: 24890609
• UNSPSC Code: 12352200
• MDL number: MFCD00077311
• Assay: ≥98% (HPLC)
• Form: solid

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: DMSO: 24 mg/mL
• storage temp.: −20°C
• SMILES string: Cl[H].NCCNS(=O)(=O)c1cccc2c(Cl)cccc12
• InChI: 1S/C12H13ClN2O2S.ClH/c13-11-5-1-4-10-9(11)3-2-6-12(10)18(16,17)15-8-7-14;/h1-6,15H,7-8,14H2;1H
• InChI key: VWAGIWCLJAQLAL-UHFFFAOYSA-N

Descrizione

Biochem/physiol Actions

Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (K_i = 80 μM), casein kinase II (K_i = 5.1 μM), myosin light chain kinase (K_i = 7.4 μM), protein kinase A (K_i = 4.3 μM), protein kinase C (K_i= 47 μM), and protein kinase G (K_i = 3.8 μM).

Informazioni sulla sicurezza

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves