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A0608

ABL1 (27-end), active, His-tagged from mouse

Name: ABL1 (27-end), active, His-tagged from mouse
Brand: SIGMA
Price: 416 CHF

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sinonimo/i:

JTK7, c-ABL, p150, v-abl

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Voi/SKU	Disponibilità	Prezzo
10 μg	Per conoscere la disponibilità, visualizza il carrello	CHF 416.00

Informazioni su questo articolo

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD00675018

Specific activity:

717-971 nmol/min·mg

Assay:

≥70% (SDS-PAGE)

Recombinant:

expressed in baculovirus infected Sf9 cells

CHF 416.00

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Proprietà

recombinant

expressed in baculovirus infected Sf9 cells

Quality Segment

200

product line

PRECISIO^® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

717-971 nmol/min·mg

mol wt

~135 kDa

UniProt accession no.

P00520

shipped in

dry ice

storage temp.

−70°C

Gene Information

mouse ... Abl1(11350)

Descrizione

Biochem/physiol Actions

ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of ABL protein is negatively regulated by its SH3 domain and deletion of the SH3 domain turns ABL1 into an oncogene. Translocation and head-to-tail fusion of the BCR and ABL1 genes is present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDK1-mediated phosphorylation, suggesting a cell cycle function for ABL1.

Physical form

Supplied in 50mM NaPhosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1mM PMSF, 0.2 mM DTT, 25% glycerol

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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Questo articolo	SRP5279	HPA028409	SAB4501044
Sigma-Aldrich A0608 ABL1 (27-end), active, His-tagged from mouse	Sigma-Aldrich SRP5279 ABL1, active, His tagged human	Sigma-Aldrich HPA028409 Anti-ABL1 antibody produced in rabbit	Sigma-Aldrich SAB4501044 Anti-ABL antibody produced in rabbit
description PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution	description PRECISIO^®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description affinity isolated antibody
assay ≥70% (SDS-PAGE)	assay ≥70% (SDS-PAGE)	assay -	assay -
specific activity 717-971 nmol/min·mg	specific activity 663-1024 nmol/min·mg	specific activity -	specific activity -
Gene Information mouse ... Abl1(11350)	Gene Information human ... ABL1(25)	Gene Information human ... ABL1(25)	Gene Information human ... ABL1(25)
form buffered aqueous glycerol solution	form buffered aqueous glycerol solution	form buffered aqueous glycerol solution	form buffered aqueous solution
recombinant expressed in baculovirus infected Sf9 cells	recombinant expressed in baculovirus infected Sf9 cells	recombinant -	recombinant -
storage temp. −70°C	storage temp. −70°C	storage temp. −20°C	storage temp. −20°C

Pittogrammi

GHS08,GHS07

Parola di avvertenza

Danger

Codici di pericolo

H315,H319,H360D

Avvertenze di sicurezza

P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Che succede?

WGK 1

Punto di infiammabilità (°F)

Not applicable

Punto di infiammabilità (°C)

Not applicable

DPI (dispositivi di protezione individuale)

Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificati d'analisi (COA)

Lot/Batch Number

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