95200

Vitamin B_12a hydrochloride

≥96% (UV), ≥96% (HPLC)

• Sinonimo/i: Hydroxocobalamin hydrochloride
• Formula empirica (notazione di Hill): C₆₂H₈₉CoN₁₃O₁₅P · HCl
• Numero CAS: 59461-30-2
• Peso molecolare: 1382.82
• Numero CE: 261-772-4
• Numero MDL: MFCD00167463
• Codice UNSPSC: 12352205
• ID PubChem: 57653658
• NACRES: NA.79

Proprietà

• Origine biologica: fermentation/recombinant
• Livello qualitativo: 100
• Saggio: ≥96% (HPLC); ≥96% (UV)
• Forma fisica: powder or crystals
• Perdita: ≤12% loss on drying, 20 °C (HV)
• Colore: red to dark red
• Solubilità: methanol: 10 mg/mL at 20 °C, clear, dark red
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: Cl.C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2N([Co+]O)C1=C(C)C3=NC(=CC4=NC(=C(C)C5=N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78
• InChI: 1S/C62H90N13O14P.ClH.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H;;1H2/q;;+3;/p-3/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;;/m1.../s1; KEHNCSYXYMMUCO-BXSGNKEGSA-K

Descrizione

Applicazioni

Vitamin B12a hydrochloride has been used as an antidote for cyanide poisoning.

Azioni biochim/fisiol

Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.

Altre note

Review

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)