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88185

Tetrazole solution

~0.45 M in acetonitrile, solution, suitable for DNA synthesis, filtered through a 1 μm filter

Tetrazole solution

Sinonimo/i:

1H-Tetrazole

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A voi/SKUDisponibilitàPrezzo
100 mL

Disponibile per la spedizione OGGIdaBuchs

CHF 195.00
500 mL

Disponibile per la spedizione OGGIdaBuchs

CHF 799.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
CH2N4
Numero CAS:
Peso molecolare:
70.05
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
105799
Technique(s):
DNA synthesis: suitable
Bp:
84 °C (lit.)

CHF 195.00


Disponibile per la spedizione OGGIDettagli


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Nome del prodotto

Tetrazole solution, suitable for DNA synthesis, filtered through a 1 μm filter, ~0.45 M in acetonitrile

form

liquid

Quality Segment

quality

filtered through a 1 μm filter

concentration

~0.45 M in acetonitrile

technique(s)

DNA synthesis: suitable

impurities

≤0.003% water

bp

84 °C (lit.)

mp

156-158 °C (lit.)

density

0.798 g/mL at 20 °C

SMILES string

c1nnn[nH]1

InChI

1S/CH2N4/c1-2-4-5-3-1/h1H,(H,2,3,4,5)

InChI key

KJUGUADJHNHALS-UHFFFAOYSA-N

General description

The product is ~0.45M solution of tetrazole in acetonitrile. Tetrazole ring plays significant role in various synthetic and industrial processes.

Application

Tetrazole solution is useful for DNA synthesis. It may be employed as a catalyst for the in situ synthesis of deoxyribonucleoside phosphoramidites.[1] It may be used in the preparation of following anionic nucleotide-lipids:[2]
  • thymidine 3′-(1,2-dilauroyl-sn-glycero-3-phosphate) , diC12-3′-dT
  • thymidine 3′-(1,2-dimyristoyl-sn-glycero-3-phosphate) diC14- 3′-dT
  • thymidine-3′-(1,2-dipalmitoyl-sn-glycero-3-phosphate) diC16- 3′-dT

Other Notes

Catalyst used in the phosphite triester method of oligonucleotide synthesis for the coupling of (dialkylamino)phosphines[3]

Disclaimer

Saturated solution at room temperature; storage below room temperature causes precipitation.

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Questo articolo
8.57000L03300034442
BTT Activator 0.3 M

Sigma-Aldrich

L033000

BTT Activator

Acetonitrile suitable for DNA synthesis, ≥99.9% (GC)

Sigma-Aldrich

34442

Acetonitrile

technique(s)

DNA synthesis: suitable

technique(s)

-

technique(s)

-

technique(s)

DNA synthesis: suitable, cDNA synthesis: suitable

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

100

form

liquid

form

solution

form

-

form

liquid

bp

84 °C (lit.)

bp

81.6 °C/1013 hPa (Acetonitrile)

bp

-

bp

81-82 °C (lit.)

density

0.798 g/mL at 20 °C

density

-

density

-

density

0.786 g/mL at 25 °C (lit.)

impurities

≤0.003% water

impurities

-

impurities

-

impurities

≤0.0001% free alkali (as NH3), ≤0.001% free acid (as CH3COOH), ≤0.001% water (Karl Fischer)


pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Classe di stoccaggio

3 - Flammable liquids

wgk

WGK 3

flash_point_f

41.0 °F - closed cup

flash_point_c

5 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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