73156

N-Methyl-L-serine

≥98% (TLC)

• Sinonimo/i: (S)-3-Hydroxy-2-(methylamino)propionic acid, N-Me-Ser-OH
• Formula empirica (notazione di Hill): C₄H₉NO₃
• Numero CAS: 2480-26-4
• Peso molecolare: 119.12
• Beilstein: 2498641
• Numero MDL: MFCD00037756
• Codice UNSPSC: 12352202
• ID PubChem: 329764666
• NACRES: NA.32

Proprietà

• Saggio: ≥98% (TLC)
• Stato: powder
• Attività ottica: [α]/D +9.5±1.0°, c = 1 in 1 M HCl
• Composizione: carbon, 39.5-41.1% ; nitrogen, 11.5-12.0%
• Colore: white
• Punto di fusione: 204 °C
• Stringa SMILE: CN[C@@H](CO)C(O)=O
• InChI: 1S/C4H9NO3/c1-5-3(2-6)4(7)8/h3,5-6H,2H2,1H3,(H,7,8)/t3-/m0/s1; PSFABYLDRXJYID-VKHMYHEASA-N

Descrizione

Azioni biochim/fisiol

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease[1], neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue. N-Methyl-L-serine stimulates hyaluronan production in human skin fibroblasts[2].

N-Methyl-L-serine has been found to stimulate production of high molecular mass hyaluronan in human fibroblasts. This effect was specific to methylated L-serine and not observed with other methylated amino acids. [2]

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable