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Merck
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Key Documents

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48756

Sigma-Aldrich

Genistin

≥97.5% (TLC)

Sinonimo/i:

4′,5,7-Trihydroxyisoflavone 7-glucoside, Genistein 7-glucoside, Genistein-7-O-β-D-glucopyranoside, Genistoside, NSC 5112

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About This Item

Formula empirica (notazione di Hill):
C21H20O10
Numero CAS:
529-59-9
Peso molecolare:
432.38
Beilstein:
64479
Numero MDL:
MFCD00016883
Codice UNSPSC:
41116107
ID PubChem:
57651161
NACRES:
NA.77

Saggio

≥97.5% (TLC)

Temperatura di conservazione

−20°C

Stringa SMILE

OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C(=COc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m1/s1
ZCOLJUOHXJRHDI-CMWLGVBASA-N

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Azioni biochim/fisiol

Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT), with no measurable effect on mammalian or microbial DNA polymerases.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Slide 1 of 6

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Daidzin analytical standard

Supelco

42926

Daidzin

Daidzein ≥98%, synthetic

Sigma-Aldrich

D7802

Daidzein

Genistein analytical standard

Supelco

92136

Genistein

Daidzein analytical standard

Supelco

16587

Daidzein

Diosmin analytical standard

Supelco

61386

Diosmin

α-Ketoglutaric acid 99.0-101.0% (T)

Sigma-Aldrich

75890

α-Ketoglutaric acid

Vladimir Ajdžanović et al.
The Journal of membrane biology, 239(3), 131-135 (2010-12-07)
A decrease of erythrocyte membrane fluidity can contribute to the pathophysiology of hypertension. Soy products, which are used as alternative therapeutics in some cardiovascular conditions, contain various isoflavones (genistein, daidzein, and their glucosides, genistin and daidzin), which can incorporate cellular
Soha M Hamdy et al.
Toxicology and industrial health, 28(8), 746-757 (2011-11-18)
Breast cancer is the second leading cause of cancer death among women and the third most common cancer. In this study, we investigated the chemoprevention efficacy of each of soy genistin, selenium or a combination of them against breast cancer.
Anna Hsu et al.
Experimental biology and medicine (Maywood, N.J.), 235(1), 90-97 (2010-04-21)
Previous studies have suggested that soy isoflavones exert anticarcinogenic effects against prostate cancer. We propose that soy extracts, containing a mixture of soy isoflavones and other bioactive components, would be a more potent chemo-preventive agent than individual soy isoflavones. We
Bo Yuan et al.
Journal of agricultural and food chemistry, 60(6), 1428-1436 (2012-01-20)
The chemical forms in which isoflavones appear in food or supplements seem to play an important role in their absorption efficiency. However, the influence of the chemical form of isoflavones on their plasma disposition has never been reported, although the
Lun-Cheng Kuo et al.
Applied microbiology and biotechnology, 94(5), 1181-1188 (2012-02-22)
In order to produce isoflavone aglycosides effectively, a process of isoflavone hydrolysis by Bacillus subtilis natto NTU-18 (BCRC 80390) was established. This process integrates the three stages for the production of isoflavone aglycosides in one single fermenter, including the growth
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