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30153

Sigma-Aldrich

Potassium 2-mercaptoethanesulfonate

≥95% (T)

Sinonimo/i:

2-Mercaptoethanesulfonic acid potassium salt, Coenzyme M potassium salt, MES potassium salt

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About This Item

Formula condensata:
HSCH2CH2SO3K
Numero CAS:
126397-51-1
Peso molecolare:
180.29
Numero MDL:
MFCD17215943
Codice UNSPSC:
12352200
ID PubChem:
329753443

Saggio

≥95% (T)

Temperatura di conservazione

−20°C

Stringa SMILE

[K+].[O-]S(=O)(=O)CCS

InChI

1S/C2H6O3S2.K/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1
XXZMREMZWJKGRQ-UHFFFAOYSA-M

Applicazioni

2-Mercaptoethanesulfonic acid salts (Coenzyme M potassium salt, MESK) are used as an antioxidant and cytoprotective agent in a wide variety of applications from protection from toxicity of therapeutic agents, such as cyclophosphamide and to prevention of brain injury damage.

Azioni biochim/fisiol

Metabolite in microbial metabolism in diverse environments and methane metabolism ; methanogens use 2-mercaptoethanesulfonate (CoM; coenzyme M) as the terminal methyl carrier in methano-genesis; can be determined with chemiluminescence detection by flow injection analysis.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Consigli di prudenza

P261 - P305 + P351 + P338

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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A A Garcia
The Annals of pharmacotherapy, 29(6), 590-591 (1995-06-01)
To report a case of possible ifosfamide-induced Fanconi syndrome in and adult with cancer. A 20-year old man was treated for an osteosarcoma with a chemotherapy regimen that included ifosfamide, methotrexate, and doxorubicin. Three months after completing therapy he developed
M J Wargovich et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 5(5), 355-360 (1996-05-01)
We assessed the effects of 41 potential chemopreventive agents in the F344 rat using the inhibition of carcinogen-induced aberrant crypt foci (ACF) in the colon as the measure of efficacy. ACF were induced by the carcinogen azoxymethane in F344 rats
L F Capitán-Vallvey et al.
Talanta, 51(6), 1155-1161 (2008-10-31)
A flow injection method with chemiluminescence (CL) detection is proposed for the determination of sodium 2-mercaptoethane sulfonate (MESNA), a drug often used to reduce the urotoxic effects of antineoplastic alkylating agents. The procedure is based on the reaction of the
The protective effect of 2-mercaptoethane sulfonate (MESNA) against traumatic brain injury in rats.
Yilmaz ER, Kertmen H, et al.
Acta Neurochirurgica (2012)

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