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236M-9

Sigma-Aldrich

CEA (CEA31) Mouse Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

CEA31, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (236M-94)
vial of 0.5 mL concentrate (236M-95)
bottle of 1.0 mL predilute (236M-97)
vial of 1.0 mL concentrate (236M-96)
bottle of 7.0 mL predilute (236M-98)

Produttore/marchio commerciale

Cell Marque™

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG1

Controllo

colon

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

cytoplasmic

Informazioni sul gene

human ... CEACAM5(1048)

Categorie correlate

Descrizione generale

Anti-CEA is an antibody against carcinoembryonic antigen (CEA), a protein thought to promote tumor development through its role as a cell adhesion molecule. Anti-CEA positivity is seen in adenocarcinomas of many origins, especially colon and lung adenocarcinomas, but is rarely seen in mesothelial cells and mesotheliomas.

Qualità


IVD
IVD
IVD
RUO

Linkage

CEA Positive Control Slides, Product No. 236S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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V L Go
Cancer, 37(1 suppl), 562-566 (1976-01-01)
Carcinoembryionic antigen (CEA) a glycoprotein extracted from colonic cancer tissue (beta-globulin electrophoretic mobility, sedimentation coefficient 7 to 8S, and mol wt approximately 200,000) can be detected and measured by radioimmunoassay. Clinical evaluations of CEA determination have given the following results:
H Kamino et al.
Cancer, 61(6), 1142-1148 (1988-03-15)
Forty nasopharyngeal carcinomas (NPC) were studied by immunohistochemistry using an antibody to involucrin and the following three keratin antibodies: (1) an antibody to low molecular weight keratin reactive with nonsquamous epithelium, (2) a high molecular weight keratin antibody reactive with
V Tron et al.
Archives of pathology & laboratory medicine, 111(3), 291-293 (1987-03-01)
Immunohistologic markers have been of considerable value in differentiating malignant mesothelioma from adenocarcinoma. Recently, staining for milk-fat globule (MFG) protein has been suggested as a useful diagnostic test for this separation, but subsequent reports have been conflicting, with some authors
J H Lagendijk et al.
Journal of clinical pathology, 52(4), 283-290 (1999-09-04)
To discriminate between adenocarcinomas that are primary to the ovary and metastatic to the ovary, especially of colonic and breast origin, by immunohistochemistry, using stepwise discriminant analysis or a decision tree. 312 routinely processed, formalin fixed tissue specimens were used.
Julu Bhatnagar et al.
Anticancer research, 22(3), 1849-1857 (2002-08-10)
Although the prognostic value of Carcinoembryonic antigen (CEA) in colorectal cancer follow-up is well known, CEA expression in esophageal cancer is not widely recognized and studies correlating tissue CEA expression in stomach cancers with tumor differentiation have yielded contradictory results.
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