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14158

Sigma-Aldrich

Sodium succinate dibasic hexahydrate

BioUltra, ≥99.0% (NT)

Sinonimo/i:

Butanedioic acid disodium salt, Succinic acid disodium salt

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About This Item

Formula condensata:
NaOOCCH2CH2COONa · 6H2O
Numero CAS:
6106-21-4
Peso molecolare:
270.14
Beilstein:
3921044
Numero CE:
205-778-7
Numero MDL:
MFCD00149117
Codice UNSPSC:
12161700
ID PubChem:
57647136

Nome Commerciale

BioUltra

Saggio

≥99.0% (NT)

Impurezze

insoluble matter, passes filter test

pH

8.0-9.5 (25 °C, 1 M in H2O)

Solubilità

H2O: 1 M at 20 °C, clear, colorless

Anioni in tracce

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

Cationi in tracce

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

Assorbanza UV

λ: 260 nm Amax: 0.080
λ: 280 nm Amax: 0.045

Stringa SMILE

O.O.O.O.O.O.[Na+].[Na+].[O-]C(=O)CCC([O-])=O

InChI

1S/C4H6O4.2Na.6H2O/c5-3(6)1-2-4(7)8;;;;;;;;/h1-2H2,(H,5,6)(H,7,8);;;6*1H2/q;2*+1;;;;;;/p-2
ZBTUYCUNQBRXOR-UHFFFAOYSA-L

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Applicazioni

Sodium succinate dibasic hexahydrate can be used to study x-ray crystallography, protein structural analysis, proteomics and optimization reagents. Sodium succinate dibasic hexahydrate has been used to determine the calorimetric and diffractometric evidence for the sequential crystallization of buffer components and the consequential pH swing in frozen solutions. Sodium succinate dibasic hexahydrate has also been used to provide insights into the mechanism of Pseudomonas dacunhae aspartate β-decarboxylase from rapid-scanning stopped-flow kinetics.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
BCBC7728
BCBC7728V
BCBD9373V
BCBC7731V
BCBC7731

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Prakash Sundaramurthi et al.
The journal of physical chemistry. B, 114(14), 4915-4923 (2010-03-23)
Sequential crystallization of succinate buffer components in the frozen solution has been studied by differential scanning calorimetry and X-ray diffractometry (both laboratory and synchrotron sources). The consequential pH shifts were monitored using a low-temperature electrode. When a solution buffered to
Robert S Phillips et al.
Biochemistry, 49(24), 5066-5073 (2010-05-18)
The mechanism of wild-type and R37A mutant Pseudomonas dacunhae aspartate beta-decarboxylase (ABDC) was studied by rapid-scanning stopped-flow spectrophotometry. Mixing wild-type ABDC with 50 mM disodium l-Asp resulted in the formation of a 325 nm absorption peak within the dead time
Jun Kimura et al.
Cancer science, 104(8), 1083-1090 (2013-05-18)
Pancreatic cancer has a poor prognosis after complete macroscopic resection combined with chemotherapy. Even after neoadjuvant chemotherapy, R0 resection is often not possible. Moreover, current imaging techniques cannot reliably distinguish viable cancer cells from scar tissue at the resectional margin.
Ilya B Zavodnik et al.
Life sciences, 92(23), 1110-1117 (2013-05-07)
The present study was designed for further evaluation of the biochemical mechanism of hepatic mitochondrial dysfunction under oxidative damages induced by organic hydroperoxide, tert-butyl hydroperoxide (tBHP), for estimation of the molecular targets impaired during oxidative stress, and for investigation of
Hiroshi Yoneyama et al.
Anti-cancer drugs, 26(1), 90-100 (2014-09-05)
The efficacy of gemcitabine (GEM), a standard treatment agent for pancreatic cancer, is insufficient because of primary or acquired resistance to this drug. Patients with tumors intrinsically sensitive to GEM gradually acquire resistance and require a shift to second agents

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