104-05A

Human Epidermal Melanocytes: HEM, adult

• Sinonimo/i: HEM cells
• Codice UNSPSC: 41106514
• NACRES: NA.81

Proprietà

• Origine biologica: human skin (normal abdominal)
• Livello qualitativo: 100
• Confezionamento: pkg of 500,000 cells
• Produttore/marchio commerciale: Cell Applications, Inc
• Modalità di accrescimento: Adherent
• Cariotipo: 2n = 46
• Morfologia: Epidermal
• tecniche: cell culture | mammalian: suitable
• Malattie correlate: metabolic disorders
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −196°C

Descrizione

Descrizione generale

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Epidermal melanocytes are pigment-producing cells located at the basal level of epidermis, where they interact with keratinocytes via cellular processes called dendrites. Melanin, the pigment produced by melanocytes and responsible for skin color, is then transferred to keratinocytes, where it is stored in vesicles called melanosomes located around the nucleus to provide protection from UV radiation. HEM maintain their characteristic shape in culture for many generations. They produce melanin and serve as a useful cell model for the studies of melanocyte proliferation and differentiation, as well as progression of melanocytic neoplasia.

Origine della linea cellulare

Skin

Applicazioni

melanin production, melanocyte proliferation, differentiation

Componenti

Basal Medium containing 30% FBS & 10% DMSO

Nota sulla preparazione

• 2nd passage, >500,000 cells in Basal Medium containing 30% FBS & 10% DMSO
• Can be cultured at least 12 doublings

Mantenimento delle subcolture

Please refer to the HEM Culture Protocol.

Esclusione di responsabilità

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable