7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

Name: 7-Amino-4-methyl-3-coumarinacetic acid <I>N</I>-succinimidyl ester
Brand: SIGMA
Price: 416 CHF

BioReagent, suitable for fluorescence, ≥90% (HPLC)

Sinonimo/i:

7-(Dimethylamino)coumarin-4-acetic acid-NHS, 7-Amino-4-methyl-3coumarinylacetyl, N-Succinimidyl 7-amino-4-methyl-3-coumarinylacetate, AMCA-NHS, Succinimidyl-7-amino-4-methylcoumarin-3-acetate

Slide 1 of 1

Autenticati per visualizzare i prezzi organizzativi e contrattuali.

Scegli un formato

08450-5MG

CHF 416.00

Per conoscere la disponibilità, visualizza il carrello

Richiedi un ordine in blocco

Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₆H₁₄N₂O₆

Numero CAS:

113721-87-2

Peso molecolare:

330.29

NACRES:

NA.32

PubChem Substance ID:

329748586

UNSPSC Code:

12352108

MDL number:

MFCD00036170

Beilstein/REAXYS Number:

9007679

Documenti fondamentali

Visualizza tutta la documentazione

Vai a

Servizio Tecnico

Hai bisogno di aiuto? Il nostro team di scienziati qualificati è a tua disposizione.

Permettici di aiutarti

product line

BioReagent

Quality Level

100

assay

≥90% (HPLC)

solubility

DMF: soluble, DMSO: soluble

fluorescence

λ_ex 354 nm; λ_em 440 nm in methanol

suitability

suitable for fluorescence

storage temp.

−20°C

InChI

1S/C16H14N2O6/c1-8-10-3-2-9(17)6-12(10)23-16(22)11(8)7-15(21)24-18-13(19)4-5-14(18)20/h2-3,6H,4-5,7,17H2,1H3

InChI key

ILKQVTIMOGNSAS-UHFFFAOYSA-N

Confronta articoli simili

Visualizza il confronto per intero

Mostra le differenze

1 of 4

Questo articolo	36801	55156	03-32-1501
Sigma-Aldrich 08450 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester	Sigma-Aldrich 36801 7-(Diethylamino)coumarin-3-carboxylic acid N-succinimidyl ester	Sigma-Aldrich 55156 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester	Sigma-Aldrich 03-32-1501 Z-Phe-Arg-7-amido-4-methylcoumarin, Hydrochloride
suitability suitable for fluorescence	suitability -	suitability suitable for fluorescence	suitability -
fluorescence λ_ex 354 nm; λ_em 440 nm in methanol	fluorescence λ_ex 445 nm; λ_em 482 nm in 0.1 M phosphate pH 7.0	fluorescence λ_ex 386 nm; λ_em 448 nm in 0.1 M Tris pH 9.0	fluorescence -
solubility DMF: soluble, DMSO: soluble	solubility DMF: soluble, DMSO: soluble, acetonitrile: soluble	solubility DMF: soluble, DMSO: soluble	solubility 5% acetic acid: 1 mg/mL, DMSO: 1 mg/mL, water: 1 mg/mL
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 200
assay ≥90% (HPLC)	assay ≥96.0% (HPLC)	assay ≥95.0% (coupling assay to aminopropyl silica gel)	assay ≥98% (HPLC)

Application

AMCA-NHS has been utilized in the development of a donor europium chelate fluorochrome for use in LRET based analyses by first reacting with an amino group and then with DTPA anhydride . Utilized in FRET based studies, acting as the donor dye and can be paired with fluorescein-5-isothiocyanate as the acceptor dye . A blue fluorescent dye reactive towards primary amine groups on proteins, peptides, antibodies, and other biomolecules (at pH 7.0-9.0).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Labeling of lysyl residues in proteins[1]

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

BCCC8914

BCCB8681

423080/1

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Reactivity of lysyl residues on the (Ca(2+)-Mg2+)-ATPase to 7-amino-4-methylcoumarin-3-acetic acid succinimidyl ester.

H I Stefanova et al.

Biochemistry, 32(1), 356-362 (1993-01-12)

The (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum was labeled with the succinimidyl ester of 7-amino-4-methylcoumarin-3-acetic (AMCA). Although a large number of residues were labeled, it was found that Lys-492 was labeled preferentially at pH values between 6 and 8, consistent with an

Questions

Reviews

No rating value

Active Filters

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica