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933856

Sigma-Aldrich

γ-Valerolactone

greener alternative

BioRenewable, anhydrous, DMF and NMP substitute, ≥99%

Sinonimo/i:

4,5-Dihydro-5-methyl-2(3H)-furanone, GVL, γ-Methyl-γ-butyrolactone, 4,5-Dihydro-5-methyl-2(3H)-furanone, 4-Hydroxypentanoic acid lactone

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About This Item

Formula empirica (notazione di Hill):
C5H8O2
Numero CAS:
Peso molecolare:
100.12
Beilstein:
80420
Numero MDL:
Codice UNSPSC:
12352100
NACRES:
NA.21
Prezzi e disponibilità al momento non sono disponibili

Densità del vapore

3.45 (vs air)

Livello qualitativo

Saggio

≥99%

Stato

liquid

Caratteristiche più verdi

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Impurezze

≤50 ppm water

Colore

colorless to light yellow

Indice di rifrazione

n20/D 1.432 (lit.)

P. ebollizione

207-208 °C (lit.)
82-85 °C/10 mmHg (lit.)

Punto di fusione

−31 °C (lit.)

Densità

1.05 g/mL at 25 °C (lit.)

Categoria alternativa più verde

Stringa SMILE

CC1CCC(=O)O1

InChI

1S/C5H8O2/c1-4-2-3-5(6)7-4/h4H,2-3H2,1H3
GAEKPEKOJKCEMS-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

We are committed to providing environmentally friendly products, and γ-Valerolactone (GVL) is a prime example of our dedication to this effort. GVL is a bio-based solvent derived from renewable sources, which makes it a sustainable alternative to traditional organic solvents like NMP and DMF. GVL aligns with the principles of "Use of Renewable Feedstocks" and "Safer Solvents and Auxiliaries" and offers exceptional solubility properties. As a result, it is an effective solvent for various applications, such as chemical synthesis. GVL is non-toxic, non-irritating, and biodegradable, making it a safe and eco-friendly choice for both consumers and the environment. Overall, γ-Valerolactone is an excellent option for companies and researchers seeking to reduce their environmental footprint while still delivering high-quality products.

Applicazioni

  • Peptide synthesis
  • Cross-coupling reactions
  • Nonaqueous redox-flow batteries
  • Polymerization reaction
  • Extraction

Caratteristiche e vantaggi

  • Bio-based
  • Made from Renewable Resource - rice
  • Biodegradable
  • Non-toxic
  • Low vapor pressure

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

204.8 °F - closed cup

Punto d’infiammabilità (°C)

96 °C - closed cup


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γ-Valerolactone (GVL): An eco-friendly anchoring solvent for solid-phase peptide synthesis
Musaimi O A, et al.
Tetrahedron Letters, 60, 151058-151058 (2019)
γ-Valerolactone as a Green Solvent for Extracting Carboxylic Acids and Alcohols from n-Tetradecane: Equilibrium Data for Model Systems at 298.15 K
Carlos E. S. Dantas and Roberta Ceriani
Journal of Chemical and Engineering Data, Volume 67, Issue 6, 1460?1473-1460?1473 (2022)
Greening Fmoc/tBu solid-phase peptide synthesis
Musaimi O A, et al.
Green Chemistry, 22, 996-1018 (2020)
Nonaqueous redox-flow batteries: organic solvents, supporting electrolytes, and redox pairs
Ke Gong, Qianrong Fang, Shuang Gu, Sam Fong Yau Li and Yushan Yan
Energy & Environmental Science, 8, 3515-3530 (2015)
Green solid-phase peptide synthesis 4. γ-Valerolactone and N-formylmorpholine as green solvents for solid phase peptide synthesis
Kumar A, et al.
Tetrahedron Letters, 58, 2986-2988 (2017)

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Contatta l'Assistenza Tecnica.