46648

Praziquantel

VETRANAL^®, analytical standard

• Sinonimo/i: 2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
• Formula empirica (notazione di Hill): C₁₉H₂₄N₂O₂
• Numero CAS: 55268-74-1
• Peso molecolare: 312.41
• Beilstein: 761557
• Numero CE: 259-559-6
• Numero MDL: MFCD00058531
• Codice UNSPSC: 41116107
• ID PubChem: 329756613
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 200
• Nome Commerciale: VETRANAL^®
• Durata: limited shelf life, expiry date on the label
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Spettro attività antibiotica: parasites
• applicazioni: clinical testing
• Formato: neat
• Modalità d’azione: cell membrane | interferes
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4
• InChI: 1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2; FSVJFNAIGNNGKK-UHFFFAOYSA-N

Descrizione

Descrizione generale

Chemical structure: quinolone

Praziquantel (PZQ) is a pyrazino-isoquinoline compound used as a broad-spectrum anthelmintic drug against trematode and cestode infections.[1][2]

Applicazioni

PZQ may be used as a reference standard for the determination for PZQ in:

• Surface water samples by solid phase extraction (SPE) and ultra-high performance liquid chromatography-quadrupole linear ion trap tandem mass spectrometry (UHPLC-QqLIT-MS) equipped with electrospray ionization (ESI) source.[3]
• Plants by HPLC with triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS/MS) operating in multiple reaction monitoring (MRM) mode.[4]
• Tablet formulations[5][6] by reversed phase (RP) HPLC with ultraviolet (UV) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Indicazioni di pericolo: H412
• Consigli di prudenza: P273 - P501
• Classi di pericolo: Aquatic Chronic 3
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)