37019

Atropine

analytical standard

• Sinonimo/i: Hyoscyamine, Tropine tropate, endo-(±)-α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
• Formula empirica (notazione di Hill): C₁₇H₂₃NO₃
• Numero CAS: 51-55-8
• Peso molecolare: 289.37
• Beilstein: 91260
• Numero CE: 200-104-8
• Numero MDL: MFCD00022622
• Codice UNSPSC: 85151701
• ID PubChem: 329755584
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Durata: limited shelf life, expiry date on the label
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• applicazioni: cleaning products; cosmetics; food and beverages; personal care
• Formato: neat
• Temperatura di conservazione: −20°C
• Stringa SMILE: CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
• InChI: 1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?; RKUNBYITZUJHSG-SPUOUPEWSA-N
• Informazioni sul gene: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

Descrizione

Descrizione generale

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.
For the analysis of the phytotoxins.

Applicazioni

Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Azioni biochim/fisiol

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Ricostituzione

Dried down, ~100μg/mL after reconstitution with 1 mL of water

Risultati analitici

purity : ≥96.0% (HPLC)

Note legali

Extrelut is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H300 + H330
• Consigli di prudenza: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• Classi di pericolo: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable