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31673

Supelco

4,4′-Methylene-bis(2-chloroaniline)

analytical standard

Sinonimo/i:

2,2′-Dichloro-4,4′-methylenedianiline, 4,4′-Diamino-3,3′-dichlorodiphenylmethane

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About This Item

Formula condensata:
CH2[C6H3(Cl)NH2]2
Numero CAS:
101-14-4
Peso molecolare:
267.15
Beilstein:
1882318
Numero CE:
202-918-9
Numero MDL:
MFCD00047829
Codice UNSPSC:
41116107
ID PubChem:
329753879

Grado

analytical standard

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

P. ebollizione

202-214 °C/0.3 mmHg (lit.)

Punto di fusione

102-107 °C (lit.)

applicazioni

cleaning products
cosmetics
food and beverages
personal care

Formato

neat

Stringa SMILE

Nc1ccc(Cc2ccc(N)c(Cl)c2)cc1Cl

InChI

1S/C13H12Cl2N2/c14-10-6-8(1-3-12(10)16)5-9-2-4-13(17)11(15)7-9/h1-4,6-7H,5,16-17H2
IBOFVQJTBBUKMU-UHFFFAOYSA-N

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Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Avvertenza

Restricted to professional users. Attention − Avoid exposure − obtain special instructions before use.

Avvertenze

Danger

Indicazioni di pericolo

H302,H341,H350,H410

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Muta. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

235.4 °F - closed cup

Punto d’infiammabilità (°C)

113 °C - closed cup

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Certificati d'analisi (COA)

Lot/Batch Number

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Evaluation of worker exposure to TDI, MOCA, and methylene chloride.
Richard Fairfax et al.
Journal of occupational and environmental hygiene, 3(6), D50-D53 (2006-04-20)
P Vineis et al.
Cancer causes & control : CCC, 8(3), 346-355 (1997-05-01)
Epidemiological evidence on the relation between aromatic amines and cancer risk is reviewed. In particular, cancer risk in humans resulting from exposure to aromatic amines from occupational sources and tobacco smoking is assessed with reference to ecologic, cohort, and case-control
T M Reid et al.
Toxicology letters, 95(3), 205-210 (1998-08-15)
The genotoxic potential of two occupationally significant chemicals, 4,4'-methylene-bis-2-chloroaniline (MOCA) and 2-phenyl-1,4-benzoquinone (PBQ), was explored by monitoring the induction of mutations at the HPRT locus of AHH-1 human lymphoblastoid cells. Exposure of AHH-1 cells to the putative carcinogenic metabolite of
A Jeżewska et al.
Toxicology mechanisms and methods, 21(7), 554-560 (2011-04-09)
A new procedure has been developed for the assay of 2,2'-dichloro-4,4'-methylenedianiline (MOCA) using high-performance liquid chromatography with diode array detector. MOCA was sampled from workplace air and derivative before determination using 3,5-dinitrobenzoyl chloride. The determination was carried out in the
Hong-I Chen et al.
Urology, 66(2), 305-310 (2005-08-16)
Transitional cell carcinoma of the urinary bladder is associated with occupational exposure to 4,4'-methylenebis(2-chloroaniline) (MBOCA). A program to monitor MBOCA levels in the work environment and to screen for bladder cancer was performed at four MBOCA manufacturing factories. The U.S.
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